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Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase 1 Isoform 3

Known as: Truncated INPP5D, Short-SHIP, SIP-110 
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 3 (976 aa, ~109 kDa) is encoded by the human INPP5D gene. This protein plays a role… Expand
National Institutes of Health

Papers overview

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2016
2016
Background: Diabetes mellitus Type 1 (T1DM) is associated with metabolic and microvascular diseases as part of a multi-organ and… Expand
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2016
2016
Isolation of prostate stem cells (PSCs) is crucial for understanding their biology during normal development and tumorigenesis… Expand
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2015
2015
Understanding normal and cancer stem cells should provide insights into the origin of prostate cancer and their mechanisms of… Expand
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2011
2011
In a recessive ENU mutagenesis screen for embryonic lethality, we identified a mouse pedigree with a missense mutation of SHIP1… Expand
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Highly Cited
2010
Highly Cited
2010
Mammary stem cells (MaSCs) play critical roles in normal development and perhaps tumorigenesis of the mammary gland. Using… Expand
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2006
2006
Embryonic stem (ES) cells are pluripotent cells that have the ability to either self-renew or differentiate into any cell type… Expand
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2005
2005
The s-SHIP protein is a shorter isoform of the longer SHIP1 protein and lacks the N-terminal SH2 domain region contained in SHIP1… Expand
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2001
2001
SH2-containing inositol 5'-phosphatase (SHIP) modulates the activation of immune cells after recruitment to the membrane by Shc… Expand
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1997
1997
An inositol polyphosphate-5-phosphatase (SIP-110) that binds the SH3 domains of the adaptor protein GRB2 was produced in Sf9… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Shc and Grb2 form a complex in cells in response to growth factor stimulation and link tyrosine kinases to Ras during… Expand
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