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Phase 0 Trial

Known as: Phase 0, Pre-Clinical Trial 
A clinical trial that uses an investigational agent that is available only in very limited quantities and which has never previously given to humans… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Gaming behaviour with Pokémon GO and physical activity: A preliminary study with medical students in Thailand
Pokémon GO becomes the most rapidly downloaded mobile application in history. This study aimed to determine the physical activity… 
2017
2017
Paroxysmal atrioventricular block: Electrophysiological mechanism of phase 4 conduction block in the His‐Purkinje system: A comparison with phase 3 block
Paroxysmal atrioventricular (A‐V) block is relatively rare, and due to its transient nature, it is often under recognized. It is… 
2011
2011
Phase 0 Clinical Chemoprevention Trial of the Akt Inhibitor SR13668
SR13668, an orally active Akt pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies. To… 
Highly Cited
2008
Highly Cited
2008
Oncologic Phase 0 Trials Incorporating Clinical Pharmacodynamics: from Concept to Patient
The U.S. Food and Drug Administration recently issued an Exploratory Investigational New Drug (IND) guidance that provides a… 
2004
2004
The Rehabilitation Results of Hemiplegic Patients
The aim of this study was to determine whether or not there was an improvement in the daily life activities and ambulation levels… 
Review
2003
Review
2003
FACTORS INFLUENCING THE FRONT END OF THE INNOVATION PROCESS : A COMPREHENSIVE REVIEW OF SELECTED EMPIRICAL NPD AND EXPLORATIVE FFE STUDIES
In this paper we construct and propose an empirical-based research framework for the so-called “Fuzzy Front End” (FFE) of the… 
1985
1985
Progesterone-synthesizing ability of preovulatory follicles of cows relative to the peak of LH.
Preovulatory cow follicles (n = 34) were collected at different times after the onset of oestrus until shortly before ovulation… 
1982
1982
STUDIES ON THE BRADYCARDIA INDUCED BY BEPRIDIL
1 Bepridil, a novel active compound for prophylactic treatment of anginal attacks, induced persistent bradycardia and a non… 
1981
1981
Supraventricular Antidysrhythmic and Electrophysiological Effects of Bepridil, a New Antianginal Agent
Summary We investigated the potential antidysrhythmic effects of bepridil, a new antianginal agent, on dysrhythmias of… 
1976
1976
Effects of tritium-labeled pyrimidine nucleosides on epithelial cell proliferation in the mouse. I. Cytodynamic perturbations in normal circadian rhythms after a single injection of 3H-thymidine.
In a combined stathmokinetic, autoradiographic, and microspectrophotometric study on the cytodynamics in mouse epidermis… 
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