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Pharmacogenomics Biomarker Domain

Known as: PB, Pharmacogenomics Biomarker 
A special purpose domain and reference dataset that associates observed genetic mutations with medical conclusions (e.g. disease diagnosis, drug… 
National Institutes of Health

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CDISC SDTM Submission Domain Abbreviation TerminologyClinical Data Interchange Standards Consortium Terminology

Papers overview

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2011
2011
Lead contents in the surface enamel of primary and permanent teeth, whole blood, serum, and saliva of 6- to 8-year-old children.
2010
2010
X-ray fluorescence with synchrotron radiation to elemental analysis of lead and calcium content of primary teeth.
Highly Cited
2008
Highly Cited
2008
Toxicogenomics of water chemistry influence on chronic lead exposure to the fathead minnow (Pimephales promelas).
2007
2007
Minority-variant pfcrt K76T mutations and chloroquine resistance, Malawi.
Genotyping of the chloroquine-resistance biomarker pfcrt (Plasmodium falciparum chloroquine resistance transporter gene) suggests… 
2005
2005
The CYP2B2 phenobarbital response unit contains binding sites for hepatocyte nuclear factor 4, PBX-PREP1, the thyroid hormone receptor beta and the liver X receptor.
A 163 bp enhancer in the CYP2B2 5' flank confers PB (phenobarbital) inducibility and constitutes a PBRU (PB response unit). The… 
2005
2005
Leukaemia‐Derived Dendritic Cells Can Be Generated From Blood or Bone Marrow Cells From Patients With Myelodysplasia: A Methodological Approach Under Serum‐Free Culture Conditions
Functional dendritic cells (DC) are professional antigen‐presenting cells (APC) and can be generated in vitro from healthy as… 
1996
1996
Regulation of HLA-DR and invariant chain expression by human peripheral blood mononuclear cells with lead, interferon-gamma, or interleukin-4.
It has been reported that the expression of major histocompatibility complex (MHC) class II can be regulated by lead (Pb) in… 
1996
1996
SRTIO3 BUFFERING EFFECT ON PB1-XLAXTIO3 THIN FILMS PREPARED BY PULSED LASER DEPOSITION
Thin films of phase‐pure perovskite PLT (Pb0.95La0.05Ti0.9875O3) were deposited in situ onto Si, Pt/Ti/SiO2/Si, and SrTiO3/Si… 
1991
1991
Lead influences translational or posttranslational regulation of Ia expression and increases invariant chain expression in mouse B cells.
The molecular mechanisms governing the increased cell surface expression of major histocompatibility complex (MHC) class II… 
1982
1982
Hippocampal mossy fiber pathway development in normal and postnatally lead-exposed rats
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