Share This Author
The Structural Basis of Monoclonal Antibody Alz50's Selectivity for Alzheimer's Disease Pathology*
The results suggest that tau adopts a distinct conformation when polymerized into filaments and that this conformation is recognized selectively by Alz50.
Deepwater Horizon crude oil impacts the developing hearts of large predatory pelagic fish
- J. Incardona, L. Gardner, N. Scholz
- Environmental ScienceProceedings of the National Academy of Sciences
- 24 March 2014
It is shown that environmentally realistic exposures to crude oil cause specific dose-dependent defects in cardiac function in all three species, with circulatory disruption culminating in pericardial edema and other secondary malformations.
High rates of HCO3– secretion and Cl– absorption against adverse gradients in the marine teleost intestine: the involvement of an electrogenic anion exchanger and H+-pump metabolon?
- M. Grosell, E. Mager, C. Williams, J. Taylor
- Environmental Science, BiologyJournal of Experimental Biology
- 1 June 2009
H+-V-ATPase activity hyperpolarizes the apical membrane potential that provides the driving force for apical electrogenic nHCO3–/Cl– exchange, which appears to occur against both Cl– and H CO3– electrochemical gradients.
Basolateral NBCe1 plays a rate-limiting role in transepithelial intestinal HCO3– secretion, contributing to marine fish osmoregulation
- J. Taylor, E. Mager, M. Grosell
- Biology, Environmental ScienceJournal of Experimental Biology
- 1 February 2010
High levels of intestinal tract expression of a basolateral Na+/HCO3– cotransporter of the electrogenic NBCe1 isoform in toadfish is confirmed, which shows elevated expression following salinity challenge, indicating its importance in marine fish osmoregulation.
Acute embryonic or juvenile exposure to Deepwater Horizon crude oil impairs the swimming performance of mahi-mahi (Coryphaena hippurus).
It is shown that brief exposure of a water-accommodated fraction of oil from the spill to mahi-mahi as juveniles, or as embryos/larvae that were then raised to juvenile stage, reduces their swimming performance.
Influence of bicarbonate and humic acid on effects of chronic waterborne lead exposure to the fathead minnow (Pimephales promelas).
Impacts of Deepwater Horizon crude oil exposure on adult mahi‐mahi (Coryphaena hippurus) swim performance
- J. Stieglitz, E. Mager, Ronald H. Hoenig, D. Benetti, M. Grosell
- Environmental ScienceEnvironmental toxicology and chemistry
- 1 October 2016
It is demonstrated that acute exposure to a sublethal concentration of the water accommodated fraction of Deepwater Horizon crude oil results in significant swim performance impacts on young adult mahi-mahi, representing the first report of acute sublethal toxicity on adult pelagic fish in the Gulf of Mexico following the spill.
Influences of water chemistry on the acute toxicity of lead to Pimephales promelas and Ceriodaphnia dubia.
The effects of weathering and chemical dispersion on Deepwater Horizon crude oil toxicity to mahi-mahi (Coryphaena hippurus) early life stages.
CXC chemokines and their receptors are expressed in type II cells and upregulated following lung injury.
- J. Vanderbilt, E. Mager, L. Dobbs
- Biology, MedicineAmerican journal of respiratory cell and…
- 26 June 2003
It is shown that freshly isolated alveolar Type II (TII) cells express three of the major proinflammatory CXC chemokines (GRO, CINC-2alpha, and MIP-2) and their cognate receptor CXCR2 and this support a central role for the TII cell as an immunologic effector cell in the alveolus.