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Phage Display

Molecular biology technique that facilitates cloning or identification of specific proteins or peptides with a specific antigenic, ligand or protein… 
National Institutes of Health

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Related topics

3 relations
BacteriophagesPeptide Library

Broader (1)

Genetic Techniques

Papers overview

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Review
2009
Review
2009
Antibody phage display : methods and protocols
Table of Contents Preface Contributors Antibody phage display - overview of a powerful technology that has quickly translated to… 
Highly Cited
2006
Highly Cited
2006
Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM.
2005
2005
Isolation and structural analysis of peptide mimotopes for the disialoganglioside GD2, a neuroblastoma tumor antigen.
Highly Cited
2001
Highly Cited
2001
Phage display epitope mapping of human neutrophil flavocytochrome b558. Identification of two juxtaposed extracellular domains.
Despite extensive experimental and clinical evidence demonstrating the critical role of flavocytochrome b558 (Cyt b) in the NADPH… 
Highly Cited
2000
Highly Cited
2000
Identification of efficiently cleaved substrates for HIV-1 protease using a phage display library and use in inhibitor development.
The recognition sequences for substrate cleavage by aspartic protease of HIV-1 are diverse and cleavage specificities are… 
Highly Cited
1999
Highly Cited
1999
Generation of native bovine mAbs by phage display.
Modeling of disease pathogenesis and immunity often is carried out in large animals that are natural targets for pathogens of… 
Highly Cited
1998
Highly Cited
1998
Directed selection of MIP-1α neutralizing CCR5 antibodies from a phage display human antibody library
The seven trans-membrane chemokine receptor CCR-5 is a coreceptor for macrophage tropic HIV-1 strains. CCR-5 responds to a number… 
Highly Cited
1998
Highly Cited
1998
Improving the affinity and the fine specificity of an anti-cortisol antibody by parsimonious mutagenesis and phage display.
Immunoassays are widely used to determine steroid concentrations. However, they are limited by the specificity of antisteroid… 
Review
1997
Review
1997
Structural and mechanistic determinants of affinity and specificity of ligands discovered or engineered by phage display.
The scope and utility of phage display is reviewed with emphasis on medical applications and structure-based ligand and drug… 
Highly Cited
1996
Highly Cited
1996
Selection of Linkers for a Catalytic Single-chain Antibody Using Phage Display Technology*
Phage display has been evaluated as a means of rapidly selecting tailored linkers for single-chain antibodies (scFvs) from… 
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