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National Institutes of Health

Papers overview

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Review
2019
Review
2019
Nivolumab plus ipilimumab versus sunitinib in first-line treatment for advanced renal cell carcinoma: extended follow-up of efficacy and safety results from a randomised, controlled, phase 3 trial.
BACKGROUND In the ongoing phase 3 CheckMate 214 trial, nivolumab plus ipilimumab showed superior efficacy over sunitinib in… Expand
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Review
2019
Review
2019
European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (TaT1 and Carcinoma In Situ) - 2019 Update.
CONTEXT This overview presents the updated European Association of Urology (EAU) guidelines for non-muscle-invasive bladder… Expand
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Review
2019
Review
2019
Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
BACKGROUND Patients with a germline BRCA1 or BRCA2 mutation make up a small subgroup of those with metastatic pancreatic cancer… Expand
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Review
2019
Review
2019
Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised…
Summary Background After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction… Expand
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Review
2019
Review
2019
Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.
BACKGROUND Patients who have unresectable or metastatic melanoma with a BRAF V600E or V600K mutation have prolonged progression… Expand
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Review
2017
Review
2017
The vasoprotective axes of the renin‐angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases
&NA; The renin‐angiotensin system (RAS) is undisputedly one of the most prominent endocrine (tissue‐to‐tissue), paracrine (cell… Expand
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Review
2017
Review
2017
Predictive Accuracy : A Misleading Performance Measure for Highly Imbalanced Data
The most commonly reported model evaluation metric is the accuracy. This metric can be misleading when the data are imbalanced… Expand
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Highly Cited
2007
Highly Cited
2007
Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy.
The Ribosomal Database Project (RDP) Classifier, a naïve Bayesian classifier, can rapidly and accurately classify bacterial 16S… Expand
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Highly Cited
2002
Highly Cited
2002
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
BACKGROUND Type 2 diabetes affects approximately 8 percent of adults in the United States. Some risk factors--elevated plasma… Expand
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Highly Cited
1994
Highly Cited
1994
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved for the alignment… Expand
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