• Publications
  • Influence
The use and misuse of FTIR spectroscopy in the determination of protein structure.
Fourier transform infrared (FTIR) spectroscopy is an established tool for the structural characterization of proteins. However, many potential pitfalls exist for the unwary investigator. In thisExpand
  • 1,336
  • 34
  • PDF
Fourier Self-Deconvolution: A Method for Resolving Intrinsically Overlapped Bands
The general theory of Fourier self-deconvolution, i.e., spectral deconvolution using Fourier transforms and the intrinsic lineshape, is developed. The method provides a way of computationallyExpand
  • 1,125
  • 18
Infrared spectroscopy of biomolecules
Theoretical Analyses of the Amide I Infrared Bands of Globular Proteins (H. Torii & M. Tasumi). Fourier Transform Infrared Spectroscopy of Enzyme Systems (J. Alben). Light--Induced Fourier TransformExpand
  • 651
  • 18
  • PDF
New insight into protein secondary structure from resolution-enhanced infrared spectra.
  • 1,028
  • 15
Polymorphic phase behaviour of phospholipid membranes studied by infrared spectroscopy.
  • 632
  • 13
Phospholipid phase transitions in model and biological membranes as studied by infrared spectroscopy.
Fourier transform infrared (FT-IR) spectroscopy is an extremely powerful yet non-perturbing physical technique for monitoring the conformation and dynamics of all portions of the phospholipidExpand
  • 412
  • 13
Beware of proteins in DMSO.
The effect on the secondary structure of representative alpha-helical, beta-sheet and disordered proteins by varying concentrations of dimethyl sulphoxide (DMSO) in 2H2O has been investigated byExpand
  • 214
  • 9
Beware of connective tissue proteins: assignment and implications of collagen absorptions in infrared spectra of human tissues.
Infrared spectra of human central nervous system tissue and human breast carcinoma are presented. The spectra are discussed in terms of the composition of the tissues. It is shown that differencesExpand
  • 329
  • 8
Infrared spectra of basal cell carcinomas are distinct from non-tumor-bearing skin components.
Infrared spectroscopy, by probing the molecular vibration of chemical bonds, directly indicates tissue biochemistry. An expanding body of literature suggests that infrared spectra distinguishExpand
  • 144
  • 6