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Perforin:ACnc:Pt:WBC:Qn

Known as: Perforin:ACnc:Pt:Leucoc:Qn, perforina:concentración arbitraria:punto en el tiempo:leucocito:cuantitativo:, Perforin:SçKons:Zml?:Lökosit:Kant 
National Institutes of Health

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ACncChemical procedureLeukocytesperforin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer
The survival of prostate cancer (PrCa) patients is associated with the transition to hormone-independent tumor growth and… 
Review
2013
Review
2013
Structure and function of perforin, pathophysiology of human perforin deficiency and perforin inhibitors as potential therapeutics
Perforin is a 67kDa pore-forming protein secreted by CTL/NK cells to induce the death of virus-infected and transformed cells… 
2012
2012
Assembly and Regulation of the Membrane Attack Complex Based on Structures of C 5 b 6 and sC 5 b 9
Michael A. Hadders,1,7,8 Doryen Bubeck,2,7 Pietro Roversi,3 Svetlana Hakobyan,4 Federico Forneris,1 B. Paul Morgan,4 Michael K… 
2011
2011
Rapamycin does not control hemophagocytic lymphohistiocytosis in LCMV‐infected perforin‐deficient mice
Hemophagocytic lymphohistiocytosis (HLH) is an immunodysregulatory disorder for which more effective treatments are needed. The… 
2005
2005
Potential of real-time PCR assessment of granzyme B and perforin up-regulation for rejection monitoring in intestinal transplant recipients.
2004
2004
Dimethyl 2,2-dichlorovinyl phosphate (DDVP) markedly inhibits activities of natural killer cells, cytotoxic T lymphocytes and lymphokine-activated killer cells via the Fas-ligand/Fas pathway in…
Highly Cited
2000
Highly Cited
2000
Acidic pH inhibits non-MHC-restricted killer cell functions.
Immunotherapeutic strategies in advanced stages of solid tumors have generally met with little success. Various mechanisms have… 
Highly Cited
1999
Highly Cited
1999
Tumor regression after adoptive transfer of effector T cells is independent of perforin or Fas ligand (APO-1L/CD95L).
The adoptive transfer of tumor-specific effector T cells can result in complete regression and cure mice with systemic melanoma… 
Highly Cited
1997
Highly Cited
1997
Immunosensitization of prostate carcinoma cell lines for lymphocytes (CTL, TIL, LAK)-mediated apoptosis via the Fas-Fas-ligand pathway of cytotoxicity.
Several reports suggest that immunotherapy mediated by cytotoxic lymphocytes is beneficial in the destruction of drug-resistant… 
1990
1990
The lysis of cytotoxic T lymphocytes and their blasts by cytotoxic T lymphocytes.
After binding to their targets, cytotoxic T lymphocytes (CTL) deliver a lethal hit signal, ultimately leading to target cell… 
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