• Publications
  • Influence
Production and characterization of keratinase of a feather-degrading Bacillus licheniformis PWD-1.
TLDR
The keratinase produced by Bacillus licheniformis PWD-1 was induced by feather powder and was stable from pH 5 to 12.5, and the relative activity of this enzyme toward casein, feather powder, keratin, elastin, and collagen was 100:52:41:18:7.
NF-κB Activity Is Required for the Deregulation of c-myc Expression by the Immunoglobulin Heavy Chain Enhancer*
TLDR
Results indicate that the NF-κB/Rel transcription factors play an important role in the deregulation of the translocated c-myc gene in Burkitt's lymphoma and suggest that interference with NF-σB function may represent a new approach to the treatment of Burkitt’s lymphoma.
Redundancy of C/EBP alpha, -beta, and -delta in supporting the lipopolysaccharide-induced transcription of IL-6 and monocyte chemoattractant protein-1.
TLDR
The activities of C/EBP alpha, -beta, and -delta are redundant in regard to the expression of IL-6 and monocyte chemoattractant protein-1 to lymphoblasts, which normally lack C/ EBP factors and do not display LPS induction of proinflammatory cytokines.
Genomic organization, expression, and chromosome localization of a third aurora-related kinase gene, Aie1.
TLDR
Findings suggest that Aie1 plays a role in spermatogenesis, and the entire intron-exon organization of the Aie2 gene is reported, which conform to the consensus sequences (GT/AG) of the splicing donor and acceptor sites of most eukaryotic genes.
Gene-modified tumor vaccine with therapeutic potential shifts tumor-specific T cell response from a type 2 to a type 1 cytokine profile.
TLDR
The data suggest that the failure of unmodified D5 to generate therapeutic T cells is not due to an inability to recognize tumor Ags, but, rather, to the induction of an immune response that is ineffective in mediating tumor regression, i.e., immune deviation.
Lipofection indirectly increases expression of endogenous major histocompatibility complex class I molecules on tumor cells.
TLDR
It is proposed that lipid complex-mediated gene transfer may provide immunological advantages beyond those that are attributable to expression of the specific gene transferred when parameters optimized for gene transfer of the alloantigen were used.
Tumor regression after adoptive transfer of effector T cells is independent of perforin or Fas ligand (APO-1L/CD95L).
TLDR
Adoptive transfer of PKO and wt effector T cells provided long-term immunity to D5 and induced complete regression of pulmonary metastases and significantly prolonged survival of the treated animals regardless of their genotype.
...
1
2
...