Perazine

Known as: 10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-, Perazine [Chemical/Ingredient], Pernazine 
A phenothiazine antipsychotic with actions and uses similar to those of CHLORPROMAZINE. Extrapyramidal symptoms may be more common than other side… (More)
National Institutes of Health

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15 relations

Broader (2)

Antipsychotic AgentsDopamine Antagonists

Narrower (6)

Dolo-TensilanPERAZINE DIMALONATEPerazine MaleateTaxilan
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In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

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2013
2013
Elevated clozapine serum levels in combination with perazine
Clozapine is a widely used atypical antipsychotic drug, mainly applied in treatment of schizophrenia. It is mainly metabolised by… (More)
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2009
2009
Perazine at therapeutic drug concentrations inhibits human cytochrome P450 isoenzyme 1A2 (CYP1A2) and caffeine metabolism--an in vitro study.
The aim of the present study was to estimate the inhibitory effect of perazine, a phenothiazine neuroleptic with piperazine… (More)
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2004
2004
The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes.
Identification of cytochrome P-450 isoenzymes (CYPs) involved in perazine 5-sulphoxidation and N-demethylation was carried out… (More)
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2000
2000
Distribution interactions between perazine and antidepressant drugs. In vivo studies.
Perazine belongs to the most frequently chosen neuroleptics for a combination with antidepressants in the therapy of complex or… (More)
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2000
2000
Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro
Rationale: Perazine (PER) is a phenothiazine antipsychotic drug frequently used in Germany that undergoes extensive metabolism… (More)
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1999
1999
Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants
Perazine, a piperazine-type phenothiazine neuroleptic, is the most frequently chosen drug for combination with antidepressants in… (More)
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1998
1998
Suicide with moclobemide and perazine
A 51-year-old woman who was diagnosed as suffering from depression was found dead in her flat. The autopsy revealed no… (More)
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Highly Cited
1992
Highly Cited
1992
Facial expression and emotional face recognition in schizophrenia and depression
Twenty-three acute schizophrenics, 21 acute major depressives (Research Diagnostic Criteria), and 15 normal controls participated… (More)
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1979
1979
Binding of tricyclic antidepressants and perazine to human plasma
The binding of amitriptyline (AT), nortriptyline (NT), imipramine (IP), desmethylimipramine (DMI) and perazine (PER) to plasma… (More)
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1969
1969
Acute hepatitis due to Herpes simplex virus in an adult.
A case is described of herpetic hepatitis in a pregnant woman with primary herpetic stomatitis. Intranuclear inclusion bodies and… (More)
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