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Perazine

Known as: 10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-, Perazine [Chemical/Ingredient], Pernazine 
A phenothiazine antipsychotic with actions and uses similar to those of CHLORPROMAZINE. Extrapyramidal symptoms may be more common than other side… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (2)

Antipsychotic AgentsDopamine Antagonists

Narrower (6)

Dolo-TensilanPERAZINE DIMALONATEPerazine MaleateTaxilan
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Main contribution of the cytochrome P450 isoenzyme 1A2 (CYP1A2) to N-demethylation and 5-sulfoxidation of the phenothiazine neuroleptic chlorpromazine in human liver--A comparison with other…
Highly Cited
2000
Highly Cited
2000
Determination of phenothiazines in human body fluids by solid-phase microextraction and liquid chromatography/tandem mass spectrometry.
Eleven phenothiazine derivatives with heavy side-chains were found to be extractable from human whole blood and urine samples by… 
1998
1998
p-Chloroamphetamine, a serotonin-releasing drug, elicited in rats a hyperglycemia mediated by the 5-HT1A and 5-HT2B/2C receptors.
1988
1988
Predictors of Neuroleptic Treatment Response in Acute Schizophrenia: Results of a Treatment Study with Perazine
In schizophrenia outcome research, it has turned out that static variables such as demographie, biographical, and c1inical data… 
1987
1987
Epidemiology of toxic delirium due to psychotropic drugs in psychiatric hospitals.
1980
1980
The contribution of α1-acid glycoprotein, lipoproteins, and albumin to the plasma binding of perazine, amitriptyline, and nortriptyline in healthy man
SummaryParameters for the binding of perazine (PER), amitriptyline (AT) and nortriptyline (NT) to plasma and to single plasma… 
1979
1979
Binding of tricyclic antidepressants and perazine to human plasma
SummaryThe binding of amitriptyline (AT), nortriptyline (NT), imipramine (IP), desmethylimipramine (DMI) and perazine (PER) to… 
Highly Cited
1978
Highly Cited
1978
Transport and storage of daunorubicin and doxorubicin in cultured fibroblasts.
Abstract For elucidation of the mechanism behind the differences in cellular accumulation of daunorubicin and doxorubicin, the… 
1974
1974
Formation of identical metabolites from piperazine- and dimethylamino-substituted phenothiazine drugs in man, rat and dog.
1972
1972
Hydrophobic and ionic interactions of phenothiazine derivatives with bovine serum albumin.
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