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Peptide Elongation Factor 2

Known as: Polypeptidyl-tRNA Translocase, EF-2, NSP100 
Encoded by human EEF2 Gene (EF-G/EF-2 Family), highly conserved 857-aa 95-kDa cytoplasmic Elongation Factor 2 is essential for protein synthesis and… Expand
National Institutes of Health

Related topics

Related topics

22 relations
B3(Fv)-PE38KDEL recombinant immunotoxinBL22 immunotoxinDT(388)IL3 fusion proteinDTA-H19 plasmid
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Papers overview

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Highly Cited
2014
Highly Cited
2014
Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses
Significance Ketamine is an NMDA receptor (NMDAR) antagonist that elicits rapid antidepressant responses in patients with… Expand
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Review
2012
Review
2012
Synaptic mechanisms underlying rapid antidepressant action of ketamine.
Recent clinical studies have demonstrated that a single subpsychotomimetic dose of ketamine, an ionotropic glutamatergic N-methyl… Expand
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Highly Cited
2012
Highly Cited
2012
Aerobic exercise alters skeletal muscle molecular responses to resistance exercise.
PURPOSE This study assessed the influence of an acute aerobic exercise bout on molecular responses to subsequent resistance… Expand
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Highly Cited
2011
Highly Cited
2011
Resistance exercise enhances the molecular signaling of mitochondrial biogenesis induced by endurance exercise in human skeletal muscle.
Combining endurance and strength training (concurrent training) may change the adaptation compared with single mode training… Expand
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Highly Cited
2011
Highly Cited
2011
Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion
Aim:  Feeding protein after resistance exercise enhances the magnitude and duration of myofibrillar protein synthesis (MPS) over… Expand
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Highly Cited
2008
Highly Cited
2008
AMPK activation attenuates S6K1, 4E-BP1, and eEF2 signaling responses to high-frequency electrically stimulated skeletal muscle contractions.
Regulation of protein translation through Akt and the downstream mammalian target of rapamycin (mTOR) pathway is an important… Expand
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Highly Cited
2007
Highly Cited
2007
Nutrient signalling in the regulation of human muscle protein synthesis.
The mammalian target of rapamycin (mTOR) and AMP-activated protein kinase (AMPK) are important nutrient- and energy-sensing and… Expand
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Highly Cited
2007
Highly Cited
2007
Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis.
Low-intensity resistance exercise training combined with blood flow restriction (REFR) increases muscle size and strength as much… Expand
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Highly Cited
2004
Highly Cited
2004
Overexpression of the Catalytic Subunit of Protein Phosphatase 2A Impairs Cardiac Function*
Reversible protein phosphorylation is an essential regulatory mechanism in many cellular functions. In contrast to protein… Expand
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Highly Cited
2002
Highly Cited
2002
Activation of AMP-Activated Protein Kinase Leads to the Phosphorylation of Elongation Factor 2 and an Inhibition of Protein Synthesis
Protein synthesis, in particular peptide-chain elongation, consumes cellular energy. Anoxia activates AMP-activated protein… Expand
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