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Peptide Elongation Factor 2

Known as: Polypeptidyl-tRNA Translocase, EF-2, NSP100 
Encoded by human EEF2 Gene (EF-G/EF-2 Family), highly conserved 857-aa 95-kDa cytoplasmic Elongation Factor 2 is essential for protein synthesis and… Expand
National Institutes of Health

Related topics

Related topics

22 relations
B3(Fv)-PE38KDEL recombinant immunotoxinBL22 immunotoxinDT(388)IL3 fusion proteinDTA-H19 plasmid
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses
Significance Ketamine is an NMDA receptor (NMDAR) antagonist that elicits rapid antidepressant responses in patients with… Expand
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Review
2012
Review
2012
Synaptic mechanisms underlying rapid antidepressant action of ketamine.
Recent clinical studies have demonstrated that a single subpsychotomimetic dose of ketamine, an ionotropic glutamatergic N-methyl… Expand
Highly Cited
2011
Highly Cited
2011
Resistance exercise enhances the molecular signaling of mitochondrial biogenesis induced by endurance exercise in human skeletal muscle.
Combining endurance and strength training (concurrent training) may change the adaptation compared with single mode training… Expand
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Highly Cited
2011
Highly Cited
2011
Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion
Aim:  Feeding protein after resistance exercise enhances the magnitude and duration of myofibrillar protein synthesis (MPS) over… Expand
Highly Cited
2007
Highly Cited
2007
Nutrient signalling in the regulation of human muscle protein synthesis
The mammalian target of rapamycin (mTOR) and AMP‐activated protein kinase (AMPK) are important nutrient‐ and energy‐sensing and… Expand
Highly Cited
2007
Highly Cited
2007
Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis.
Low-intensity resistance exercise training combined with blood flow restriction (REFR) increases muscle size and strength as much… Expand
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Highly Cited
2004
Highly Cited
2004
Overexpression of the Catalytic Subunit of Protein Phosphatase 2A Impairs Cardiac Function*
Reversible protein phosphorylation is an essential regulatory mechanism in many cellular functions. In contrast to protein… Expand
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Highly Cited
2002
Highly Cited
2002
Activation of AMP-Activated Protein Kinase Leads to the Phosphorylation of Elongation Factor 2 and an Inhibition of Protein Synthesis
Protein synthesis, in particular peptide-chain elongation, consumes cellular energy. Anoxia activates AMP-activated protein… Expand
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Highly Cited
1987
Highly Cited
1987
Ca2+/calmodulin‐dependent phosphorylation of elongation factor 2
Incubation of a ribosome‐free extract of rabbit reticulocytes or rat liver with [γ‐32P]ATP and Ca2+ results in incorporation of… Expand
Highly Cited
1986
Highly Cited
1986
Protein kinase C as a component of a nerve growth factor-sensitive phosphorylation system in PC12 cells.
The treatment of PC12 cells with either nerve growth factor or phorbol 12-myristate 13-acetate caused a decrease in the… Expand
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