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BL22 immunotoxin
Known as:
RFB4(dsFv)-PE38 Immunotoxin
, BL22 Immunotoxin [RFB4(dsFv)-PE38]
, BL22
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A recombinant immunotoxin consisting of the Fv portion of the anti-CD22 antibody RFB4 fused to a fragment of Pseudomonas exotoxin-A with potential…
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National Institutes of Health
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Related topics
Related topics
9 relations
Broader (2)
Antibodies
Enterotoxins
B-Lymphocytes
NCIt Antineoplastic Agent Terminology
Peptide Elongation Factor 2
Positive Regulation of Apoptosis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Investigation of the Complex Culture Medium Composition for Improved Production of ONTAK Immunotoxin by Recombinant Escherichia Coli
M. Heydari
,
S. M. Robatjazi
,
M. Zeinoddini
2015
Corpus ID: 70402981
Background and Objective: In recent years, the biological methods have been considered as a most promising candidate for the…
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2014
2014
In vitro and in vivo studies of antitumor effects of the recombinant immunotoxin MSH-PE38KDEL on melanoma.
Q. Hui
,
J. Ma
,
+8 authors
S. Lu
Neoplasma (Bratislava)
2014
Corpus ID: 29462172
MSH-PE38KDEL is a chimeric molecule composed of MSH, and fused to a truncated mutant form of Pseudomonas exotoxin (PE38KDEL). Our…
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2012
2012
Production of recombinant A254-GMCSF immunotoxin by a non-lytic insect cell expression and evaluation of its cytotoxicity by in vitro studies
A. Jahanian-Najafabadi
,
S. Bouzari
,
M. Oloomi
,
Mehryar Habibi Roudkenar
,
M. Shokrgozar
2012
Corpus ID: 82433288
Background and Aims: One of the emerging therapeutic strategies for targeted treatment of most cancers is the use of immunotoxins…
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2010
2010
Phase I trial of recombinant immunotoxin CAT-8015 (HA22) in multiply relapsed hairy cell leukemia.
R. Kreitman
,
M. Tallman
,
+7 authors
I. Pastan
2010
Corpus ID: 58502489
6523 Background: CAT-8015 (HA22) contains the Fv domains of the anti-CD22 Mab RFB4 and truncated pseudomonas exotoxin, inducing…
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2008
2008
Pharmacokinetics of recombinant immunotoxin BL22 during phase II testing in chemo-resistant hairy cell leukemia
R. Kreitman
,
W. Wilson
,
M. Stetler-stevenson
,
P. Noel
,
D. Fitzgerald
,
I. Pastan
2008
Corpus ID: 78346937
3001 Background: BL22 is a 63 kDa anti-CD22 recombinant immunotoxin containing truncated Pseudomonas exotoxin. In phase I testing…
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2007
2007
Improved Expression of Immunotoxin DT_(386)-GMCSF in E.coli
Jian-Wei Wang
2007
Corpus ID: 87312931
The development of immunotoxin DT386-GMCSF, a fusion protein which bears the N-terminal 386 amino acids of diphtheria toxin and…
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2006
2006
Minimal residual disease in hairy cell leukemia patients treated by BL22
E. Arons
,
J. Sunshine
,
+6 authors
R. Kreitman
2006
Corpus ID: 82860984
A51 Purine analogs induce long term complete remission in hairy cell leukemia (HCL) patients, but do not appear to be curative…
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2002
2002
Intravesical use of immunotoxin BDI-1-PEA for preventing the postoperative recurrence of bladder cancer
Xiao-Qing Sun
2002
Corpus ID: 77093605
Objective To study the effect of conjugate immunotoxin BDI-1-PEA given intravesically on preventing bladder cancer from recurring…
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2002
2002
GST-fusion expression of an anti-glioma recombinant immunotoxin SZ39(ScFv)-PE40 in E.coli
L. Liang
2002
Corpus ID: 101139037
Objective To express SZ39(ScFv) PE40 in the form of GST fusion protein and prepare a promising way for further investigation of…
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1995
1995
[Synthesis and properties of CD5-ricin immunotoxin].
G. Vikha
,
L. Uzhinova
,
+4 authors
R. Vasilov
Biulleten' eksperimental'noi biologii i meditsiny
1995
Corpus ID: 28437804