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Peptichemio

Known as: peptide bound m-L-sarcolysin, Peptichemio [Chemical/Ingredient], Multialchilpeptide 
A mixture of six synthetic oligopeptides in which the peptides are conjugated to metamelphalan, with alkylating and potential antineoplastic activity… 
National Institutes of Health

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Broader (2)

Antimetabolites, AntineoplasticAntineoplastic Agents, Alkylating
In BloodNCIt Antineoplastic Agent Terminologyagonistsanalogs & derivatives

Papers overview

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1985
1985
Rate of M-component changes and plasma cell labeling index in 25 patients with multiple myeloma treated with peptichemio.
Twenty-five consecutive patients with previously untreated multiple myeloma were studied for bone marrow plasma cell labeling… 
1983
1983
Inhibition of T and B lymphoblastic response by mithramycin, dacarbazine, prospidium chloride and peptichemio.
Four different cytostatic compounds (prospidium chloride, peptichemio, dacarbazine and mithramycin) have been assayed for their… 
1980
1980
A phase II study of peptichemio in advanced breast cancer
A phase II trial of Peptichemio (PTC) was conducted on 56 patients with advanced breast cancer that had been resistant to… 
1980
1980
Methotrexate-citrovorum factor used alone and in combination chemotherapy for advanced hypernephromas.
Methotrexate-citrovorum factor (MTX-CF) therapy was administered to 20 patients with advanced renal cell carcinoma. Eight… 
1979
1979
Clinical evaluation of peptichemio.
Peptichemio is a peptide complex of m-L-phenylalanine mustard. A clinical evaluation of this agent was conducted in 116 patients… 
1978
1978
Peptichemio in advanced neuroblastoma.
Peptichemio (PTC) is a mixture of six synthetic peptides of m-L-phenylalanine mustard. It acts with both alkylating and… 
1978
1978
Clinical trial of peptichemio in solid tumors of childhood.
Peptichemio (PTC) was utilized in various advanced and disseminated tumors in children. With the schedule that was used, toxicity… 
1977
1977
Lethal and kinetic effects of peptichemio on cultured human lymphoma cells.
Summary The lethal and cytokinetic effects of peptichemio (multipeptide complex of m -[di(2-chloroethyl)amino]-l-phenylalanine… 
1977
1977
Peptichemio: A new oncolytic drug in combination with vincristine and prednisolone in the treatment of non-Hodgkin lymphomas.
Peptichemio, a new oncolytic drug with alkylating and antimetabolic properties was employed in combination with vincristine and 6… 
1976
1976
Peptichemio in children with neoplastic disease.
32 children with different types of tumors have bben treated with peptichemio. The efficacy was excellent in rhabdomyosarcoma and… 
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