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Penicillanic Acid

Known as: Acid, Penicillanic, Penicillanic acids, Penicillanic Acid [Chemical/Ingredient] 
A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (22)

6,6-bis(hydroxylmethyl)penicillanate6-acetylmethylenepenicillanic acid6-chloropenicillanic acid S-sulfoxideAO 1100

Broader (1)

Anti-Bacterial Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
The realm of penicillin G acylase in β-lactam antibiotics
Review
2004
Review
2004
Recent biotechnological interventions for developing improved penicillin G acylases.
Review
1998
Review
1998
Beta-lactamase-mediated resistance and opportunities for its control.
  • D. Livermore
  • Journal of Antimicrobial Chemotherapy
  • 1998
  • Corpus ID: 17894362
Clinical use of beta-lactams has selected for beta-lactamase-producing organisms. Numerous beta-lactamases are known, and… 
1981
1981
Penicillanic acid sulfone: interaction with RTEM beta-lactamase from Escherichia coli at different pH values.
The interaction of the sulfone of penicillanic acid with the TEM-2 beta-lactamase from Escherichia coli has been investigated as… 
Highly Cited
1976
Highly Cited
1976
Mecillinam, a Novel Penicillanic Acid Derivative with Unusual Activity Against Gram-Negative Bacteria
  • H. Neu
  • Antimicrobial Agents and Chemotherapy
  • 1976
  • Corpus ID: 22221510
The in vitro activity of mecillinam, a 6 β-amidinopenicillanic acid derivative, was investigated. Mecillinam is not active… 
Highly Cited
1974
Highly Cited
1974
Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances
Three out of four workers from an antibiotic‐producing factory developed late asthma and eosinophilia on inhalation challenge… 
1973
1973
The hydrolysis of penicillin G to 6-amino penicillanic acid by entrapped penicillin acylase.
Penicillin acylase was extracted from Escherichia coli strain ATCC9637, purified and entrapped in celluose triacetate fibres. The… 
Highly Cited
1968
Highly Cited
1968
Nature and extent of penicillin side-reactions, with particular reference to fatalities from anaphylactic shock.
An appraisal is made of toxic, microbiogenic, and allergic side effects occurring in man as a result of large amounts of… 
Highly Cited
1965
Highly Cited
1965
Resistance of Escherichia coli to Penicillins I. Genetic Study of Some Ampicillin-Resistant Mutants
Eriksson-Grennberg, Kerstin G. (University of Uppsala, Uppsala, Sweden), Hans G. Boman, J. A. Torbjörn Jansson, and Sone Thorén… 
1961
1961
Action of Carbon Dioxide on 6-Amino-penicillanic Acid
THE nucleus of the penicillin molecule, 6-aminopenicillanic acid (I)1, is in some respects more stable than most penicillins (II… 
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