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Penicillanic Acid

Known as: Acid, Penicillanic, Penicillanic acids, Penicillanic Acid [Chemical/Ingredient] 
A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)
National Institutes of Health

Papers overview

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2010
2010
Class D β-lactamases represent a growing and diverse class of penicillin-inactivating enzymes that are usually resistant to… Expand
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Review
1998
Review
1998
  • D. Livermore
  • The Journal of antimicrobial chemotherapy
  • 1998
  • Corpus ID: 17894362
Clinical use of beta-lactams has selected for beta-lactamase-producing organisms. Numerous beta-lactamases are known, and… Expand
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1994
1994
Three new sulfonylamido-penicillanic acid sulfones have been prepared by reaction of 6-aminopenicillanic esters with the… Expand
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1984
1984
When penicillanic acid sulfone in large molar excess is incubated with the RTEM beta-lactamase, the enzyme becomes inactivated… Expand
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1981
1981
The interaction of the sulfone of penicillanic acid with the TEM-2 beta-lactamase from Escherichia coli has been investigated as… Expand
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Highly Cited
1976
Highly Cited
1976
  • H. Neu
  • Antimicrobial Agents and Chemotherapy
  • 1976
  • Corpus ID: 22221510
The in vitro activity of mecillinam, a 6 β-amidinopenicillanic acid derivative, was investigated. Mecillinam is not active… Expand
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Highly Cited
1974
Highly Cited
1974
Three out of four workers from an antibiotic‐producing factory developed late asthma and eosinophilia on inhalation challenge… Expand
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Highly Cited
1968
Highly Cited
1968
An appraisal is made of toxic, microbiogenic, and allergic side effects occurring in man as a result of large amounts of… Expand
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1964
1964
WHILE preparing and investigating the properties of penicillanic acid (IVa) and its derivatives, we have found that it is… Expand
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1961
1961
THE nucleus of the penicillin molecule, 6-aminopenicillanic acid (I)1, is in some respects more stable than most penicillins (II… Expand
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