Penicillanic Acid

Known as: Acid, Penicillanic, Penicillanic acids, Penicillanic Acid [Chemical/Ingredient] 
A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)
National Institutes of Health

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29 relations

Narrower (21)

6,6-bis(hydroxylmethyl)penicillanate6-acetylmethylenepenicillanic acid6-chloropenicillanic acid S-sulfoxideAO 1100
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Broader (1)

Anti-Bacterial Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

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2010
2010
Peroxisomes are required for efficient penicillin biosynthesis in Penicillium chrysogenum.
In the fungus Penicillium chrysogenum, penicillin (PEN) production is compartmentalized in the cytosol and in peroxisomes. Here… (More)
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2010
2010
Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase.
Class D β-lactamases represent a growing and diverse class of penicillin-inactivating enzymes that are usually resistant to… (More)
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2003
2003
Distinct penicillin binding proteins involved in the division , elongation , and shape of Escherichia coli K 12 ( P-lactam antibiotics / slab gel electrophoresis / binding protein mutants )
The varied effects of #-lactam antibiotics on cell division, cell elongation, and cell shape in E. coil are shown to be due to… (More)
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Review
1998
Review
1998
Beta-lactamase-mediated resistance and opportunities for its control.
Clinical use of beta-lactams has selected for beta-lactamase-producing organisms. Numerous beta-lactamases are known, and… (More)
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1997
1997
Kinetic studies on the carboxylation of 6-amino-penicillanic acid to 8-hydroxy-penillic acid
DTU Orbit (08/12/2018) Kinetic studies on the carboxylation of 6-amino-penicillanic acid to 8-hydroxy-penillic acid The… (More)
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1994
1994
Synthesis of new sulfonylamido-penicillanic acid sulfones inhibitors of beta-lactamases.
Three new sulfonylamido-penicillanic acid sulfones have been prepared by reaction of 6-aminopenicillanic esters with the… (More)
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1990
1990
Cloning, characterization of the acyl-CoA : 6-amino penicillanic acid acyltransferase gene of Aspergillus nidulans and linkage to the isopenicillin N synthase gene
The penDE gene encoding acyl-CoA:6-amino penicillanic acid acyltransferase (AAT), the last enzyme of the penicillin biosynthetic… (More)
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1981
1981
Penicillanic acid sulfone: interaction with RTEM beta-lactamase from Escherichia coli at different pH values.
The interaction of the sulfone of penicillanic acid with the TEM-2 beta-lactamase from Escherichia coli has been investigated as… (More)
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1976
1976
Mecillinam, a novel penicillanic acid derivative with unusual activity against gram-negative bacteria.
The in vitro activity of mecillinam, a 6 beta-amidinopenicillanic acid derivative, was investigated. Mecillinam is not active… (More)
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Highly Cited
1968
Highly Cited
1968
Nature and extent of penicillin side-reactions, with particular reference to fatalities from anaphylactic shock.
An appraisal is made of toxic, microbiogenic, and allergic side effects occurring in man as a result of large amounts of… (More)
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