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Penicillanic Acid

Known as: Acid, Penicillanic, Penicillanic acids, Penicillanic Acid [Chemical/Ingredient] 
A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)
National Institutes of Health

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30 relations

Narrower (22)

6,6-bis(hydroxylmethyl)penicillanate6-acetylmethylenepenicillanic acid6-chloropenicillanic acid S-sulfoxideAO 1100

Broader (1)

Anti-Bacterial Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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1984
1984
Penicillanic acid sulfone: nature of irreversible inactivation of RTEM beta-lactamase from Escherichia coli.
When penicillanic acid sulfone in large molar excess is incubated with the RTEM beta-lactamase, the enzyme becomes inactivated… 
1982
1982
Cefoxitin, N-formimidoyl thienamycin, clavulanic acid, and penicillanic acid sulfone as suicide inhibitors for different types of beta-lactamases produced by gram-negative bacteria.
Cefoxitin, N-formimidoyl thienamycin (MK0787), clavulanic acid, and penicillanic acid sulfone (CP45,899) were studied to… 
1975
1975
The chemistry of penicillanic acids. Part III. A route to 1,2-secopenicillins.
Treatment of 6β-(triphenylmethylamino)penicillanates with certain alkylating agents in the presence of strong anhydrous bases… 
1974
1974
Human Pharmacology of 6-[d-α-(3-Guanylureido)-Phenylacetamido]- Penicillanic Acid (BL-P1654)
BL-P1654 is a new α-substituted ureido penicillin which has broad-spectrum activity. Doses of 0.5 and 1.0 g administered by rapid… 
1974
1974
Beta-lactam antibiotics. I. Comparative structure--activity relationships of 6-acylaminopenicillanic acid derivatives and their 6-(D-alpha-acylaminophenylacetamido) penicillanic acid analogues.
Structure-activity relationships were compared for two series of penicillins containing a common acyl group. In series I, which… 
1971
1971
Semisynthetic penicillin 6-(D(--)-alpha-carboxy-3-thienylacetamido) penicillanic acid active against Pseudomonas in vitro.
The activity of 6-[d(-)-alpha-carboxy-3-thienylacetamido] penicillanic acid, BRL2288, was determined against Pseudomonas… 
1969
1969
Hydrolysis of phenoxymethyl penicillin into 6-amino-penicillanic acid with spores of fusaria.
Hydrolysis of phenoxymethyl penicillin into 6-aminopenicillanic acid with spores of fusaria was studied. 
1967
1967
Penicillin Acyltransferase in Penicillium chrysogenum
Isotopic exchange of 35S between penicillins and 6-amino-penicillanic acid (6-APA) was observed in cell-free extracts of… 
1964
1964
Pharmacological studies of 6 (D(-) -amino-p-hydroxyphenylacetamido) penicillanic acid in humans.
1961
1961
Action of Carbon Dioxide on 6-Amino-penicillanic Acid
THE nucleus of the penicillin molecule, 6-aminopenicillanic acid (I)1, is in some respects more stable than most penicillins (II… 
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