Patient Derived Xenograft

Known as: Patient-Derived Xenograft, PDX, Patient-Derived Xenograft Model 
The transfer of a tumor fragment from a patient into an immunodeficient mouse.
National Institutes of Health

Papers overview

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2016
2016
BACKGROUND & AIMS Pediatric liver cancer is a rare but serious disease whose incidence is rising, and for which the therapeutic… (More)
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2016
2016
Increasing evidence demonstrates the immunosuppressive kynurenine pathway's (KP) role in the pathophysiology of human gliomas. To… (More)
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2016
2016
SCLC has limited treatment options and inadequate preclinical models. Promising activity of arsenic trioxide (ASO) recorded in… (More)
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Review
2015
Review
2015
Patient-derived xenograft (PDX) models are now being widely used in cancer research and have the potential to greatly inform our… (More)
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2015
2015
The patient-derived tumor xenograft (PDTX) model has become the most realistic model for preclinical studies. PDTX models of… (More)
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2015
2015
Patient derived xenograft (PDX) models are gaining popularity in cancer research and are used for preclinical drug evaluation… (More)
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2015
2015
Neuroblastoma is a childhood tumour with heterogeneous characteristics and children with metastatic disease often have a poor… (More)
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2015
2015
We aimed to identify the factors affecting the successful tumor engraftment in breast cancer patient-derived xenograft (PDX… (More)
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Highly Cited
2015
Highly Cited
2015
Intra-tumoral genetic and functional heterogeneity correlates with cancer clinical prognoses. However, the mechanisms by which… (More)
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2014
2014
A cornerstone of preclinical cancer research has been the use of clonal cell lines. However, this resource has underperformed in… (More)
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