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Patient Derived Xenograft

Known as: Patient-Derived Xenograft, PDX, Patient-Derived Xenograft Model 
The transfer of a tumor fragment from a patient into an immunodeficient mouse.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Implantable fibrous 'patch' enabling preclinical chemo-photothermal tumor therapy.
2017
2017
Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models
Aberrant activation of histone lysine-specific demethylase (LSD1) increases tumorigenicity; hence, LSD1 is considered a… 
2017
2017
Establishment of patient-derived tumor xenograft (PDTX) models using samples from CT-guided percutaneous biopsy
This study aimed to investigate the feasibility of the establishment of a human cancer xenograft model using samples from… 
2016
2016
Gankyrin activates mTORC1 signaling by accelerating TSC2 degradation in colorectal cancer.
Review
2016
Review
2016
Patient-derived tumor xenograft models for melanoma drug discovery
ABSTRACT Introduction: Cutaneous metastatic melanoma (MM) is an aggressive form of skin cancer, with treatment providing cures to… 
2016
2016
Evaluation of anti-tumorigenic activity of BP3B against colon cancer with patient-derived tumor xenograft model
BackgroundKIOM-CRC#BP3B (BP3B) is a novel herbal prescription that is composed of three plant extracts. Our preliminary study… 
2014
2014
Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models
The patient-derived tumor xenograft (PDTX) models can reproduce a similar natural genetic background and similar biological… 
2013
2013
A patient-derived xenograft mouse model generated from primary cultured cells recapitulates patient tumors phenotypically and genetically
BackgroundPreclinical trials of cancer therapeutics require both in vitro and in vivo evaluations. Recently, a patient-derived… 
2013
2013
Patient-derived tumor xenograft model to guide the use of BRAF inhibitors in metastatic melanoma
Recently, the BRAF V600 inhibitor, vemurafenib, has revolutionized the therapeutic management of metastatic melanoma. However… 
1988
1988
Helium, tritium, and protium NMR studies of tritide-free aged PdTx.
Pulsed NMR relaxation-time measurements have been performed on PdT/sub x/, aged approximately eight years, after first removing… 
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