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miR-204 Inhibits Epithelial to Mesenchymal Transition by Targeting Slug in Intrahepatic Cholangiocarcinoma Cells
- Y. Qiu, Yong-peng Wei, +5 authors Yong-jie Zhang
- Biology, Medicine
- Cellular Physiology and Biochemistry
- 22 November 2013
The findings suggest that miR-204 plays negative roles in the invasive and/or metastatic potential of ICC, and that its suppressive effects are mediated by repressing Slug expression. Expand
Adjuvant Therapy With Capecitabine Postpones Recurrence of Hepatocellular Carcinoma After Curative Resection: A Randomized Controlled Trial
Postoperative adjuvant therapy with capecitabine is well tolerated, postpones the recurrence of HCC, and reduces the risk of tumor recurrence, and is likely to improve postoperative survival. Expand
Sorafenib extends the survival time of patients with multiple recurrences of hepatocellular carcinoma after liver transplantation
Treatment with TACE and sorafenib is worthy of further study and may have more extensive application prospects and be associated with therapeutic schedule, which was indicated by the GROUP. Expand
TGF-β upregulates miR-182 expression to promote gallbladder cancer metastasis by targeting CADM1.
- Y. Qiu, Xiang-ji Luo, +6 authors Xiao-qing Jiang
- Biology, Medicine
- Molecular bioSystems
- 4 February 2014
UNLABELLED Transforming growth factor β (TGF-β) plays important roles in tumor metastasis by regulating miRNAs expression. miR-182 is an important molecule in the regulation of cancer progression.… Expand
Sorafenib sensitizes hepatocellular carcinoma cell to cisplatin via suppression of Wnt/β-catenin signaling
It is demonstrated that sorafenib sensitizes human HCC cell to cisplatin via suppression of Wnt/β-catenin signaling, thus offering a new target for chemotherapy of HCC. Expand
[A multicenter retrospective study for the prognosis of T1b stage gallbladder carcinoma underwent different surgical procedure].
The T1b stage gallbladder carcinoma patients with cholecystectomy plus lymphadenectomy or radical choleCystectomy has improved the prognosis comparing with simple chole Cystectomy, significantly. Expand
Treatment of massive pancreaticojejunal anastomotic hemorrhage after pancreatoduodenectomy.
TAE is a safe and effective treatment modality for patients with acute hemorrhage after PDT and Vasography should be performed to locate the bleeding site. Expand
Preoperative portal vein embolization for hilar cholangiocarcinoma--a comparative study.
The results suggested that PVE is a safe and efficacious procedure in inducing adequate hypertrophy of the FLR before major hepatic resection for hilar cholangiocarcinoma with obstructive jaundice which had been relieved by percutaneous transhepatic biliary drainage. Expand
Protein phosphatase PHLPP induces cell apoptosis and exerts anticancer activity by inhibiting Survivin phosphorylation and nuclear export in gallbladder cancer
The role and mechanism of PHLPP and Survivin in GBC cells are revealed and proposed strategies for gene therapies targeting the miR-495 / PHL PP / AKT / Survivin regulatory pathway are proposed. Expand
Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models
The synergistic tumor inhibitory effect was significantly enhanced after treatments with oncolytic adenovirus expressing Hsp70 combined with CIK cells, and the anti-tumor effect was more effective for the highly malignant tumor xenografts with highly Survivin expression. Expand