Paraquat

Known as: Paraquat [Chemical/Ingredient], 4,4'-Bipyridinium, 1,1'-dimethyl-, Viologen, Methyl 
A poisonous dipyridilium compound used as contact herbicide. Contact with concentrated solutions causes irritation of the skin, cracking and shedding… (More)
National Institutes of Health

Related topics

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21 relations

Narrower (4)

GramoxoneParagreen Aducatalonmethyl viologen bis(hexafluorophosphate)

Broader (3)

HerbicidesPyridinesPyridinium Compounds
In BloodParaquat:MCnc:Pt:Bld:QnParaquat:MCnc:Pt:Gast fld:QnParaquat:MCnc:Pt:Ser/Plas:Qn
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Rotenone, Paraquat, and Parkinson’s Disease
BACKGROUND Mitochondrial dysfunction and oxidative stress are pathophysiologic mechanisms implicated in experimental models and… (More)
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Highly Cited
2009
Highly Cited
2009
Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California.
Evidence from animal and cell models suggests that pesticides cause a neurodegenerative process leading to Parkinson's disease… (More)
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Highly Cited
2008
Highly Cited
2008
Complex I is the major site of mitochondrial superoxide production by paraquat.
Paraquat (1,1'-dimethyl-4,4'-bipyridinium dichloride) is widely used as a redox cycler to stimulate superoxide production in… (More)
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Highly Cited
2002
Highly Cited
2002
Environmental Risk Factors and Parkinson's Disease: Selective Degeneration of Nigral Dopaminergic Neurons Caused by the Herbicide Paraquat
Environmental toxicants and, in particular, pesticides have been implicated as risk factors in Parkinson's disease (PD). The… (More)
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Highly Cited
2002
Highly Cited
2002
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein.
alpha-Synuclein-containing aggregates represent a feature of a variety of neurodegenerative disorders, including Parkinson's… (More)
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Highly Cited
2000
Highly Cited
2000
The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.
Experimental evidence supporting 1,1'-dimethyl-4,4'-bipyridinium [paraquat (PQ)] as a risk factor for Parkinson's disease (PD) is… (More)
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Highly Cited
1999
Highly Cited
1999
Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss
The herbicide paraquat, bearing structural similarity to the known dopaminergic neurotoxicant MPTP, has been suggested as a… (More)
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Review
1984
Review
1984
Paraquat: model for oxidant-initiated toxicity.
Paraquat, a quaternary ammonium bipyridyl herbicide, produces degenerative lesions in the lung after systemic administration to… (More)
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Highly Cited
1983
Highly Cited
1983
Glutathione and ascorbic acid in spinach (Spinacia oleracea) chloroplasts. The effect of hydrogen peroxide and of Paraquat.
The stroma of spinach chloroplasts contains ascorbic acid and glutathione at millimolar concentrations. [Reduced glutathione… (More)
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Highly Cited
1979
Highly Cited
1979
PARAQUAT POISONING: SIGNIFICANCE OF PLASMA-PARAQUAT CONCENTRATIONS
Plasma-paraquat concentrations were measured in 79 patients who had ingested liquid or granular weedkillers containing paraquat… (More)
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