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Pancreatic Intraepithelial Neoplasia-1A

Known as: PanIN-1A 
A pancreatic intraepithelial neoplasia characterized by the presence of tall columnar cells that form flat architectural patterns. Mild cytological… Expand
National Institutes of Health

Related topics

Related topics

13 relations
Epithelial CellsEpitheliumExocrine pancreasGastrointestinal system
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Serine Protease Inhibitor Kazal Type 1 Promotes Proliferation of Pancreatic Cancer Cells through the Epidermal Growth Factor Receptor
Serine protease inhibitor, Kazal type 1 (SPINK1) is expressed not only in normal human pancreatic acinar cells but also in a… Expand
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Highly Cited
2008
Highly Cited
2008
CpG island methylation profile of pancreatic intraepithelial neoplasia
Infiltrating adenocarcinoma of the pancreas is thought to develop through well-defined precursor lesions called pancreatic… Expand
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Highly Cited
2004
Highly Cited
2004
Epithelial-Cadherin and β-Catenin Expression Changes in Pancreatic Intraepithelial Neoplasia
Purpose: Cadherins and associated catenins are important mediators of epithelial cell-cell adhesion, as well as the Wnt-signaling… Expand
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Highly Cited
2003
Highly Cited
2003
p16 Inactivation in Pancreatic Intraepithelial Neoplasias (PanINs) Arising in Patients With Chronic Pancreatitis
Patients with long-standing chronic pancreatitis are thought to be at increased risk of developing pancreatic ductal… Expand
Highly Cited
2002
Highly Cited
2002
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia.
A multistep model of carcinogenesis has recently been proposed for pancreatic ductal adenocarcinomas. In this model, noninvasive… Expand
Highly Cited
2002
Highly Cited
2002
Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.
BACKGROUND & AIMS It has recently been suggested that infiltrating adenocarcinoma of the pancreas arises from histologically well… Expand
Highly Cited
2002
Highly Cited
2002
Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.
Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have… Expand
Highly Cited
2002
Highly Cited
2002
Direct Correlation between Proliferative Activity and Dysplasia in Pancreatic Intraepithelial Neoplasia (PanIN): Additional Evidence for a Recently Proposed Model of Progression
A growing body of morphological, clinical, and genetic observations suggests a progression model for pancreatic ductal… Expand
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Highly Cited
2001
Highly Cited
2001
Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia.
Pancreatic cancer (PC) is thought to develop through a series of duct lesions termed pancreatic intraepithelial neoplasia (PanIN… Expand
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Highly Cited
2000
Highly Cited
2000
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression.
Infiltrating adenocarcinomas of the pancreas are believed to arise from histologically identifiable intraductal precursors… Expand
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