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Pancreatic Intraepithelial Neoplasia-1A

Known as: PanIN-1A 
A pancreatic intraepithelial neoplasia characterized by the presence of tall columnar cells that form flat architectural patterns. Mild cytological… Expand
National Institutes of Health

Related topics

Related topics

13 relations
Epithelial CellsEpitheliumExocrine pancreasGastrointestinal system
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Papers overview

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Highly Cited
2008
Highly Cited
2008
CpG island methylation profile of pancreatic intraepithelial neoplasia
Infiltrating adenocarcinoma of the pancreas is thought to develop through well-defined precursor lesions called pancreatic… Expand
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Review
2008
Review
2008
Pancreatic Intraepithelial Neoplasia Revisited and Updated
Most pancreatic neoplasms are classified as ductal adenocarcinoma because they show a ductal phenotype, making a ductal origin… Expand
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Highly Cited
2004
Highly Cited
2004
Epithelial-Cadherin and β-Catenin Expression Changes in Pancreatic Intraepithelial Neoplasia
Purpose: Cadherins and associated catenins are important mediators of epithelial cell-cell adhesion, as well as the Wnt-signaling… Expand
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Highly Cited
2003
Highly Cited
2003
p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis.
Patients with long-standing chronic pancreatitis are thought to be at increased risk of developing pancreatic ductal… Expand
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Highly Cited
2002
Highly Cited
2002
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia.
A multistep model of carcinogenesis has recently been proposed for pancreatic ductal adenocarcinomas. In this model, noninvasive… Expand
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Highly Cited
2002
Highly Cited
2002
Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.
BACKGROUND & AIMS It has recently been suggested that infiltrating adenocarcinoma of the pancreas arises from histologically well… Expand
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Highly Cited
2002
Highly Cited
2002
Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.
Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have… Expand
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Highly Cited
2002
Highly Cited
2002
Direct Correlation between Proliferative Activity and Dysplasia in Pancreatic Intraepithelial Neoplasia (PanIN): Additional Evidence for a Recently Proposed Model of Progression
A growing body of morphological, clinical, and genetic observations suggests a progression model for pancreatic ductal… Expand
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Highly Cited
2001
Highly Cited
2001
Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia.
Pancreatic cancer (PC) is thought to develop through a series of duct lesions termed pancreatic intraepithelial neoplasia (PanIN… Expand
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Highly Cited
2000
Highly Cited
2000
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression.
Infiltrating adenocarcinomas of the pancreas are believed to arise from histologically identifiable intraductal precursors… Expand
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