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Palovarotene

An orally available, selective retinoic acid receptor gamma agonist. Palovarotene selectively binds to the gamma retinoid agonist, thereby reducing… 
National Institutes of Health

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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'
We are writing to communicate our concerns regarding the recently published study by Lees-Shepard et al. (2018). 
2019
2019
Palovarotene inhibits the development of new heterotopic ossification in fibrodysplasia ossificans progressiva (FOP)
2018
2018
Author response: Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity
2018
2018
Decision letter: Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity
2018
2018
Fibrodysplasia Ossificans Progressiva – FOP
Zusammenfassung Bei der Fibrodysplasia ossificans progressiva (FOP) besteht aufgrund einer aktivierenden Mutation im Gen für den… 
2016
2016
Positive Effects of Palovarotene on Spontaneous Heterotopic Ossification, Mobility, and Skeletal Growth in Mouse Models of FOP Reported in Journal of Bone and Mineral Research
  • 2016
  • Corpus ID: 143430101
MONTREAL, CANADA, April 14, 2016 – Clementia Pharmaceuticals Inc. today reports that the Journal of Bone and Mineral Research has… 
2015
2015
Preventative Therapeutics for Heterotopic Ossification
Abstract : HO consists of formation of ectopic bone within muscles, connective tissues and blood vessels and can cause loss of… 
Review
2015
Review
2015
G205(P) Fibrodysplasia ossificans progressiva (fop) an unfamiliar disease that is now important to diagnose
Background FOP is a rare but disabling condition characterised by congenital malformation of the great toes and progressive… 
2010
2010
The COPD Pipeline VII
Retinoids. In a landmark study (Nat Med 1997;3:675–677), Massaro and Massaro showed that elastase-induced emphysema in rats was… 
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