PXN gene

Known as: PAXILLIN, PXN, Paxillin Gene 
This gene plays a role in cytoskeleton remodeling.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Focal adhesions are large multi-protein assemblies that form at the basal surface of cells on planar dishes, and that mediate… (More)
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Review
2009
Review
2009
Src family kinases (SFKs) have a critical role in cell adhesion, invasion, proliferation, survival, and angiogenesis during tumor… (More)
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Highly Cited
2004
Highly Cited
2004
Dynamic regulation of adhesion complexes is required for cell migration and has therefore emerged as a key issue in the study of… (More)
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Highly Cited
2003
Highly Cited
2003
Cellular locomotion is driven by repeated cycles of protrusion of the leading edge, formation of new matrix adhesions and… (More)
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Highly Cited
1999
Highly Cited
1999
FAK localizes to sites of transmembrane integrin receptor clustering and facilitates intracellular signaling events. FAK-null… (More)
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Highly Cited
1999
Highly Cited
1999
Interactions between receptor tyrosine kinases of the Eph family and their ligands, ephrins, are implicated in establishment of… (More)
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Highly Cited
1999
Highly Cited
1999
In this study we have examined for molecular heterogeneity of cell-matrix adhesions and the involvement of actomyosin… (More)
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Highly Cited
1998
Highly Cited
1998
The organization of the actin cytoskeleton can be regulated by soluble factors that trigger signal transduction events involving… (More)
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Highly Cited
1995
Highly Cited
1995
The integrins have recently been implicated in signal transduction. A likely mediator of integrin signaling is focal adhesion… (More)
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Highly Cited
1992
Highly Cited
1992
Cells in culture reveal high levels of protein tyrosine phosphorylation in their focal adhesions, the regions where cells adhere… (More)
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