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PTPRT gene

Known as: KIAA0283, RPTPrho, protein tyrosine phosphatase, receptor type T 
This gene plays a role in the control of motor axon guidance.
National Institutes of Health

Related topics

Related topics

7 relations
DephosphorylationHydrolysisPTPRT protein, humanProtein dephosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
PTPRD/PTPRT mutations as potential positive predictor for response of immune checkpoint inhibitors in non-small cell lung cancer (NSCLC).
e15112Background: Immune checkpoint inhibitors (ICIs) have demonstrated positive results in non-small cell lung cancer (NSCLC… 
2018
2018
Abstract 2379: PTPRT pseudo-phosphatase domain is a denitrase that contributes to its tumor suppressor function
Department of Genetics & Genome Sciences and Case Comprehensive Cancer Center, Case Western Reserve University, 10900 Euclid… 
2016
2016
Single cell genotyping of exome sequencing-identified mutations to characterize the clonal composition and evolution of inv(16) AML in a CBL mutated clonal hematopoiesis.
2016
2016
Title Frequent promoter hypermethylation of PTPRT increases STAT 3 activation and sensitivity to STAT 3 inhibition in head and neck cancer
STAT3 overactivation is a common event in many cancers, including head and neck squamous cell carcinoma (HNSCC), where STAT3… 
2016
2016
Abstract 5243: STAT3 inhibition as chemoprevention in a chemically induced mouse model of HNSCC
Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA Background: Head and neck squamous cell… 
2015
2015
Inactivation of the Catalytic Phosphatase Domain of PTPRT/RPTPρ Increases Social Interaction in Mice
Receptor protein tyrosine phosphatase rho (RPTPρ, gene symbol PTPRT) is a transmembrane protein expressed at high levels in the… 
2014
2014
Role of PTPRT in obesity and its substrate paxillin tyrosine-88 in colorectal cancer
15 Chapter 1: Background and Significance 17 Colorectal Cancer 18 Etiology, staging, and therapy 18 Molecular basis of colorectal… 
2014
2014
Genome-wide association study identifies a putative variant in MYO3B and common variants in PTPRT associated with bovine tuberculosis: Podcast for Heredity 2014
2013
2013
PTPRT regulates the interaction of Syntaxin-binding protein 1 with Syntaxin 1 through dephosphorylation of specific tyrosine residue.
Highly Cited
2009
Highly Cited
2009
Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn
The receptor‐type protein tyrosine phosphatases (RPTPs) have been linked to signal transduction, cell adhesion, and neurite… 
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