Skip to search formSkip to main contentSkip to account menu

PTPN1 wt Allele

Known as: PTP-1B, PTP1B, Protein Tyrosine Phosphatase, Non-Receptor Type 1 wt Allele 
Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein… 
National Institutes of Health

Related topics

Related topics

11 relations
20q13.1-q13.2Cell Differentiation processCell ProliferationDephosphorylation
Expand

Broader (1)

PTPN1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The insulin-mimetic effect of Morin: a promising molecule in diabetes treatment.
2013
2013
Bioactive carbazole alkaloids from Murraya koenigii (L.) Spreng.
Highly Cited
2012
Highly Cited
2012
PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer.
The androgen receptor (AR) signaling axis plays a key role in the pathogenesis of prostate cancer. In this study, we found that… 
Review
2010
Review
2010
The two faces of PTP1B in cancer.
Review
2007
Review
2007
Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.
2005
2005
PTP1B inhibitors from Ardisia japonica
In bioassay-directed isolation from the whole plant of Ardisia japonica, sixteen known compounds: chrysophanol (1), physcion (2… 
Highly Cited
2002
Highly Cited
2002
PTP1B regulates leptin signal transduction in vivo.
2002
2002
The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates.
Inhibitors of PTP-1B could be therapeutically beneficial in the treatment of type 2 diabetes. Owing to the large number of… 
Highly Cited
1997
Highly Cited
1997
Protein-tyrosine Phosphatases PTP1B and Syp Are Modulators of Insulin-stimulated Translocation of GLUT4 in Transfected Rat Adipose Cells*
The protein-tyrosine phosphatases PTP1B and Syp have both been implicated as modulators of the mitogenic actions of insulin… 
Highly Cited
1997
Highly Cited
1997
Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License