Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 236,418,346 papers from all fields of science
Search
Sign In
Create Free Account
PTPN1 wt Allele
Known as:
PTP-1B
, PTP1B
, Protein Tyrosine Phosphatase, Non-Receptor Type 1 wt Allele
Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
11 relations
20q13.1-q13.2
Cell Differentiation process
Cell Proliferation
Dephosphorylation
Expand
Broader (1)
PTPN1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract LB-022: PTP1B directed therapeutics for HER2 positive breast cancer
Navasona Krishnan
2017
Corpus ID: 79845999
PTP1B, a validated therapeutic target for diabetes and obesity, has a critical positive role in HER2 signaling in breast…
Expand
2015
2015
Role de STAM dans la régulation endosomale de la signalisation JAK/STAT induite par les IFNs
Natacha Zanin
2015
Corpus ID: 192589813
La premiere implication des recepteurs aux interferons de type 1 (IFNAR1) dans le controle de la voie Jak/STAT induite par les…
Expand
2014
2014
Potent CDC25B and PTP1B phosphatase inhibitors: 2′,4′,6′-trihydroxylchalcone derivatives
Shui-Lian Zhao
,
Zhou Peng
,
+4 authors
Liping Guan
Medicinal Chemistry Research
2014
Corpus ID: 253648034
In this study, we examined a series of 2′,4′,6′-trihydroxychalcone derivatives for their inhibitory activity as inhibitors of…
Expand
2013
2013
PTP1B is highly induced in the presence of metformin and HCV.
A. José
,
García-Valdecasas Marta
,
Rojas Lourdes
,
R. Angela
,
Romero Manuel
2013
Corpus ID: 78295160
2013
2013
Aminostéroïdes pour le traitement d'une maladie associée à ptp1b
Michael Mclane
,
Inez Ruiz-White
,
W. L. Maloy
,
Henry R. Wolfe
2013
Corpus ID: 189186038
La presente invention concerne l'utilisation de composes aminosteroides pour l'inhibition selective de l'enzyme PTP1B chez un…
Expand
2011
2011
Employing methods of computational chemistry for the study of biochemical questions
R. Rucker
2011
Corpus ID: 192654909
Mehrere zusammenhangende biochemische Fragestellungen wurden mittels computerchemischer Techniken, insbesondere Berechnung freier…
Expand
2008
2008
Procédé de traitement du diabète
Michael Mclane
,
Inez Ruiz-White
,
Henry R. Wolfe
2008
Corpus ID: 150259323
Cette invention concerne l'utilisation de composes steroidiens pour l'inhibition selective de l'enzyme PTP1B chez un mammifere a…
Expand
2007
2007
Computational aspects of thematics: application to protein tyrosine phosphatase role in diabetes mellitus
A. A. Rao
2007
Corpus ID: 16242977
Computation plays an important role in functional genomics and proteomics. Theoretical Microscopic Titration Curves (Thematics…
Expand
2001
2001
Motif Is a Major Determinant of Substrate and Inhibitor Specificity in T-cell Protein-tyrosine Phosphatase *
E. Asante-Appiah
,
K. Ball
,
+9 authors
B. Kennedy
2001
Corpus ID: 2354404
We have studied T-cell protein-tyrosine phosphatase (TCPTP) as a model phosphatase in an attempt to unravel amino acid residues…
Expand