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PTPN1 wt Allele

Known as: PTP-1B, PTP1B, Protein Tyrosine Phosphatase, Non-Receptor Type 1 wt Allele 
Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Type-2 diabetes is a worldwidely diffuse disease characterized by insulin resistance that arises from alterations of… Expand
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2013
2013
Four new carbazole alkaloids (1-4) and fourteen known carbazole alkaloids (5-18) were isolated from Murraya koenigii. Their… Expand
Highly Cited
2012
Highly Cited
2012
The androgen receptor (AR) signaling axis plays a key role in the pathogenesis of prostate cancer. In this study, we found that… Expand
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Highly Cited
2010
Highly Cited
2010
In the course of our investigations of vanadium-containing complexes for use as insulin-enhancing agents, we have generated a… Expand
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Review
2007
Review
2007
The global epidemic of obesity and type-2 diabetes mellitus (T2DM) has highlighted the need for new therapeutic approaches. The… Expand
2005
2005
In bioassay-directed isolation from the whole plant of Ardisia japonica, sixteen known compounds: chrysophanol (1), physcion (2… Expand
Highly Cited
2002
Highly Cited
2002
Mice lacking the protein-tyrosine phosphatase PTP1B are hypersensitive to insulin and resistant to obesity. However, the… Expand
2002
2002
Inhibitors of PTP-1B could be therapeutically beneficial in the treatment of type 2 diabetes. Owing to the large number of… Expand
Highly Cited
1997
Highly Cited
1997
The protein-tyrosine phosphatases PTP1B and Syp have both been implicated as modulators of the mitogenic actions of insulin… Expand
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Highly Cited
1997
Highly Cited
1997
Insulin resistance in adipose tissue in human obesity is associated with increased protein-tyrosine phosphatase (PTPase) activity… Expand