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PTPN1 wt Allele
Known as:
PTP-1B
, PTP1B
, Protein Tyrosine Phosphatase, Non-Receptor Type 1 wt Allele
Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein…
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National Institutes of Health
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Related topics
Related topics
11 relations
20q13.1-q13.2
Cell Differentiation process
Cell Proliferation
Dephosphorylation
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Broader (1)
PTPN1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The insulin-mimetic effect of Morin: a promising molecule in diabetes treatment.
P. Paoli
,
P. Cirri
,
+4 authors
G. Camici
Biochimica et biophysica acta
2013
Corpus ID: 5301997
2013
2013
Bioactive carbazole alkaloids from Murraya koenigii (L.) Spreng.
Q. Ma
,
Jin-Ying Tian
,
+4 authors
Ya-lun Su
Fitoterapia
2013
Corpus ID: 28693605
Highly Cited
2012
Highly Cited
2012
PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer.
L. Lessard
,
D. Labbé
,
+7 authors
M. Tremblay
Cancer research
2012
Corpus ID: 207650390
The androgen receptor (AR) signaling axis plays a key role in the pathogenesis of prostate cancer. In this study, we found that…
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Review
2010
Review
2010
The two faces of PTP1B in cancer.
L. Lessard
,
M. Stuible
,
M. Tremblay
Biochimica et biophysica acta
2010
Corpus ID: 8024089
Review
2007
Review
2007
Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.
S. Koren
,
I. G. Fantus
Best practice & research. Clinical endocrinology…
2007
Corpus ID: 31600739
2005
2005
PTP1B inhibitors from Ardisia japonica
Yanfang Li
,
L. Hu
,
F. Lou
,
Jia Li
,
Q. Shen
Journal of Asian natural products research
2005
Corpus ID: 19055783
In bioassay-directed isolation from the whole plant of Ardisia japonica, sixteen known compounds: chrysophanol (1), physcion (2…
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Highly Cited
2002
Highly Cited
2002
PTP1B regulates leptin signal transduction in vivo.
J. Zabolotny
,
K. Bence-Hanulec
,
+8 authors
B. Neel
Developmental cell
2002
Corpus ID: 8909950
2002
2002
The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates.
E. Asante-Appiah
,
Sangita Patel
,
+9 authors
G. Scapin
Biochemistry
2002
Corpus ID: 23637440
Inhibitors of PTP-1B could be therapeutically beneficial in the treatment of type 2 diabetes. Owing to the large number of…
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Highly Cited
1997
Highly Cited
1997
Protein-tyrosine Phosphatases PTP1B and Syp Are Modulators of Insulin-stimulated Translocation of GLUT4 in Transfected Rat Adipose Cells*
H. Chen
,
S. Wertheimer
,
+4 authors
M. Quon
The Journal of Biological Chemistry
1997
Corpus ID: 26121102
The protein-tyrosine phosphatases PTP1B and Syp have both been implicated as modulators of the mitogenic actions of insulin…
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Highly Cited
1997
Highly Cited
1997
Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue.
F. Ahmad
,
R. Considine
,
T. L. Bauer
,
J. Ohannesian
,
C. Marco
,
B. Goldstein
Metabolism: clinical and experimental
1997
Corpus ID: 11613112
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