PTPN1 gene

Known as: PTP1B, Protein Tyrosine Phosphatase, Non-Receptor Type 1 Gene, PTPN1 
This gene plays a role in the regulation of insulin signaling and inhibition of cell growth.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Classical Hodgkin lymphoma and primary mediastinal B cell lymphoma (PMBCL) are related lymphomas sharing pathological, molecular… (More)
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2013
2013
Colorectal cancer (CRC) is one of the leading causes of cancer deaths in Western countries. A significant number of CRC patients… (More)
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2010
2010
Insulin is an inducer of brown fat adipogenesis through the activation of a signalling network that involves positive/negative… (More)
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2007
2007
BACKGROUND Protein tyrosine phosphatase 1B (PTP1B), encoded by the PTPN1 gene, efficiently dephosphorylates the insulin receptor… (More)
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2005
2005
Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, inactivates the insulin signal transduction cascade by… (More)
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2005
2005
PURPOSE This study examined the gene copy number change events at chromosome 20 in gastric cancer, and their possible… (More)
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2005
2005
The protein tyrosine phosphatase-1B, a negative regulator for insulin and leptin signalling, potentially modulates glucose and… (More)
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1998
1998
The p210 bcr-abl protein tyrosine kinase (PTK) appears to be directly responsible for the initial manifestations of chronic… (More)
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1997
1997
The protein-tyrosine phosphatases PTP1B and Syp have both been implicated as modulators of the mitogenic actions of insulin… (More)
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