FAQ

PTGR1 gene

Known as: PROSTAGLANDIN REDUCTASE 1, LTB4DH, LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2016
02420062016

Related topics

Related topics

1 relation
leukotriene B4 12-hydroxydehydrogenase

Related mentions per year

Related mentions per year

1998-2017
1990200020102020
PTGR1 gene
leukotriene B4 12-hydroxydehydrogenase

Papers overview

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2017
2017
Ptgr1 expression is regulated by NRF2 in rat hepatocarcinogenesis and promotes cell proliferation and resistance to oxidative stress.
Prostaglandin reductase-1 (Ptgr1) is an alkenal/one oxidoreductase that is involved in the catabolism of eicosanoids and lipid… (More)
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2016
2016
Knockdown of prostaglandin reductase 1 (PTGR1) suppresses prostate cancer cell proliferation by inducing cell cycle arrest and apoptosis.
Chemoresistance is a serious problem for the treatment of androgen-independent prostate cancer (PC). The underlying molecular… (More)
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2016
2016
Retracted: High Expression of PTGR1 Promotes NSCLC Cell Growth via Positive Regulation of Cyclin-Dependent Protein Kinase Complex
[This retracts the article DOI: 10.1155/2016/5230642.]. 
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2015
2015
Induction of complementary function reductase enzymes in colon cancer cells by dithiole-3-thione versus sodium selenite.
UNLABELLED Cellular induction of reductase enzymes can alter the susceptibility of cells toward drugs and chemicals. In this… (More)
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2013
2013
Quantification of acylfulvene- and illudin S-DNA adducts in cells with variable bioactivation capacities.
Illudin S and its semisynthetic analogue acylfulvene (AF) are structurally similar but elicit different biological responses. AF… (More)
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2012
2012
Up-regulation of human prostaglandin reductase 1 improves the efficacy of hydroxymethylacylfulvene, an antitumor chemotherapeutic agent.
Prostaglandin reductase 1 (PTGR1) is a highly inducible enzyme with enone reductase activity. Previous studies demonstrated the… (More)
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2011
2011
Chemical and enzymatic reductive activation of acylfulvene to isomeric cytotoxic reactive intermediates.
Acylfulvenes (AFs), a class of semisynthetic analogues of the sesquiterpene natural product illudin S, are cytotoxic toward… (More)
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2010
2010
A set of genes associated with the interferon-γ response of lung cancer patients undergoing α-galactosylceramide-pulsed dendritic cell therapy.
Invariant natural killer T (iNKT) cells possess potent antitumor effects after activation with a specific glycolipid antigen… (More)
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2008
2008
Differential gene expression patterns of the developing and adult mouse cornea compared to the lens and tendon.
The cornea continues to mature after birth to develop a fully functional, refractive and protective barrier tissue. Here we… (More)
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2006
2006
Prediction of recurrence in Ta urothelial cell carcinoma by real-time quantitative PCR analysis: a microarray validation study.
Accurate prediction of tumor recurrence in patients with superficial urothelial cell carcinoma (UCC) might result in a… (More)
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