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PTF1A gene

Known as: PANCREAS TRANSCRIPTION FACTOR 1, ALPHA SUBUNIT, bHLHa29, PTF1A 
National Institutes of Health

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TRANSCRIPTION FACTOR

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis
The contribution of cis-regulatory mutations to human disease remains poorly understood. Whole-genome sequencing can identify all… 
Highly Cited
2010
Highly Cited
2010
Proneural gene-linked neurogenesis in zebrafish cerebellum.
Highly Cited
2008
Highly Cited
2008
Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.
Highly Cited
2008
Highly Cited
2008
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas.
The mechanisms regulating pancreatic endocrine versus exocrine fate are not well defined. By analyzing the effects of Ptf1a… 
Highly Cited
2007
Highly Cited
2007
Function and regulation of zebrafish nkx2.2a during development of pancreatic islet and ducts.
Highly Cited
2007
Highly Cited
2007
Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression
We report in this study that, in the cerebellum, the pancreatic transcription factor Ptf1a is required for the specific… 
Highly Cited
2004
Highly Cited
2004
Mutations in PTF1A cause pancreatic and cerebellar agenesis
Individuals with permanent neonatal diabetes mellitus usually present within the first three months of life and require insulin… 
Highly Cited
2004
Highly Cited
2004
Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a
Dorsal and ventral pancreatic bud development from the endoderm requires inductive interactions with diverse mesodermal cell… 
Highly Cited
2004
Highly Cited
2004
Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates.
Highly Cited
2004
Highly Cited
2004
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.
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