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PTCH2 protein, human

Known as: PTC2, patched 2 protein, human, PTCH2 
Encoded by human PTCH2 Gene (Patched Family), 1203-aa transmembrane protein Patched Homolog 2 is a possible sonic hedgehog receptor, highly similar… 
National Institutes of Health

Related topics

Related topics

7 relations
Intercellular Communication ProcessPTCH2 genePTCH2 wt AlleleSignal Transduction

Broader (1)

Patched-2 Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Multi-layered mutation in hedgehog-related genes in Gorlin syndrome may affect the phenotype
Gorlin syndrome is a genetic disorder of autosomal dominant inheritance that predisposes the affected individual to a variety of… 
2014
2014
Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation.
The Patched 1 (Ptch1) receptor has a pivotal role in inhibiting the activity of the Hedgehog (Hh) pathway and is therefore… 
2013
2013
Vacuum ultraviolet photoionization studies of PtCH2 and H-Pt-CH3: a potential energy surface for the Pt+CH4 reaction.
DOI: 10.1002/anie.200((will be filled in by the editorial staff)) Methane Activation Vacuum Ultraviolet Photoionization Studies… 
2012
2012
A population-based study of hedgehog pathway gene variants in relation to the dual risk of basal cell carcinoma plus another cancer.
2007
2007
Sonic and desert hedgehog signaling in human fetal prostate development
Hedgehog signaling is thought to play an important role in rodent prostate organogenesis and morphogenesis. However, the role of… 
2006
2006
Increased apoptosis and accelerated epithelial migration following inhibition of hedgehog signaling in adaptive small bowel postresection.
The intestinal epithelium undergoes a marked adaptive response following loss of functional small bowel surface area… 
2005
2005
Low prevalence of RET rearrangements (RET/PTC1, RET/PTC2, RET/PTC3, and ELKS-RET) in sporadic papillary thyroid carcinomas in Taiwan Chinese.
Somatic rearrangement of the tyrosine kinase receptor RET is restricted to papillary thyroid carcinoma (PTC). The prevalence of… 
2003
2003
A possible paracrine hedgehog signalling pathway in neurofibromas from patients with neurofibromatosis type 1
Background  Hedgehogs (Hhs) and their receptors are involved in organ development as well as in tumorigenesis observed in basal… 
Highly Cited
2002
Highly Cited
2002
Differential interaction of Enigma protein with the two RET isoforms.
2000
2000
Involvement of the PP2C-like phosphatase Ptc2p in the DNA checkpoint pathways of Saccharomyces cerevisiae.
RAD53 encodes a conserved protein kinase that acts as a central transducer in the DNA damage and the DNA replication checkpoint… 
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