Patched-2 Receptor

Known as: Patched 2 Receptor, Patched Receptor 2, Patched Homolog-2 
A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2015
01220032015

Papers overview

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2012
2012
In January 2012, vismodegib (Erivedge; Curis/Genentech), a small-molecule inhibitor of the Hedgehog signalling pathway, was… (More)
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2011
2011
OBJECTIVE Ovarian cancer has very heterogeneous histological classification, and response to therapy of the same grade and type… (More)
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2011
2011
Receptor of Hedgehog ligands but lacks the strong capacity of PTCH1 to inhibit the signaling molecule Smoothened, which, through… (More)
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2010
2010
Sir: Compelling evidence now suggests that chordoma is derived from intraosseous notochordal remnants. Sonic hedgehog homologue… (More)
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Highly Cited
2009
Highly Cited
2009
Medulloblastoma is the most common malignant brain tumor in children. Aberrant activation of the hedgehog signaling pathway is… (More)
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2009
2009
BACKGROUND Mutations in hedgehog pathway genes, primarily genes encoding patched homologue 1 (PTCH1) and smoothened homologue… (More)
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2008
2008
We report here a three generations family with nevoid basal cell carcinoma syndrome (NBCCS) in which the diagnosis was made only… (More)
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2007
2007
Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Improving the management of rhabdomyosarcoma requires a… (More)
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2003
2003
Experimental mouse models are emerging as useful systems for the study of human brain tumors. Nuclear magnetic resonance imaging… (More)
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