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PT-141

National Institutes of Health

Related topics

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1 relation

Broader (1)

bremelanotide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Melanocortin receptors, melanotropic peptides and penile erection.
Penile erection is a complex physiologic event resulting from the interactions of the nervous system on a highly specialized… 
Review
2007
Review
2007
Melanocortins in the treatment of male and female sexual dysfunction.
Melanocortinergic agents are currently being investigated for a possible therapeutic role in male and female sexual dysfunction… 
2007
2007
Melanocortin receptors, melanotropic peptides and penile erection.
Penile erection is a complex physiologic event resulting from the interactions of the nervous system on a highly specialized… 
Highly Cited
2006
Highly Cited
2006
An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist.
INTRODUCTION Melanocortins affect multiple physiological responses, including sexual behaviors. Bremelanotide is a synthetic… 
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2005
2005
Co-administration of low doses of intranasal PT-141, a melanocortin receptor agonist, and sildenafil to men with erectile dysfunction results in an enhanced erectile response.
OBJECTIVES To evaluate the safety and pharmacodynamic effect of co-administration of subtherapeutic doses of PT-141, a cyclic… 
Highly Cited
2004
Highly Cited
2004
Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients…
PT-141, a cyclic heptapeptide melanocortin analog, was evaluated following intranasal administration in healthy male subjects and… 
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Highly Cited
2004
Highly Cited
2004
Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an…
PT-141, a cyclic heptapeptide melanocortin analog, was evaluated following subcutaneous administration to healthy male subjects… 
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Highly Cited
2004
Highly Cited
2004
Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist.
Disorders of sexual desire affect an estimated 30% of women in North America and Europe, with etiologies based on interpersonal… 
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2004
2004
Evaluation of the Safety, Pharmacokinetics and Pharmacodynamic Effects of Subcutaneously Administered PT-141, a Melanocortin Receptor Agonist, in Healthy Male Subjects and in Patients With an…
Highly Cited
2003
Highly Cited
2003
PT‐141: A Melanocortin Agonist for the Treatment of Sexual Dysfunction
Abstract: PT‐141, a synthetic peptide analogue of α‐MSH, is an agonist at melanocortin receptors including the MC3R and MC4R… 
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