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PSME3 protein, human

Known as: Ki Nuclear Autoantigen, Proteasome Activator 28 Subunit Gamma, REG-gamma 
Proteasome activator complex subunit 3 (254 aa, ~30 kDa) is encoded by the human PSME3 gene. This protein is involved in the regulation of proteasome… 
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisCell Cycle ControlCell Cycle ProgressionGenes, Regulator

Broader (1)

Ki antigen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
PA28gamma emerges as a novel functional target of tumour suppressor microRNA-7 in non-small-cell lung cancer
Background:MicroRNA-7 (miR-7) has been reported to be a tumour suppressor gene. However, whether it has a role in the growth of… 
Highly Cited
2008
Highly Cited
2008
Proteasomal Turnover of Hepatitis C Virus Core Protein Is Regulated by Two Distinct Mechanisms: a Ubiquitin-Dependent Mechanism and a Ubiquitin-Independent but PA28γ-Dependent Mechanism
ABSTRACT We have previously reported on the ubiquitylation and degradation of hepatitis C virus core protein. Here we demonstrate… 
Highly Cited
2008
Highly Cited
2008
Proteasome activator PA28γ regulates p53 by enhancing its MDM2-mediated degradation
Downregulation of p53 by MDM2‐mediated proteasomal degradation makes cells resistant to apoptosis. The MDM2–p53 interaction is… 
Highly Cited
2007
Highly Cited
2007
Involvement of the PA28gamma-dependent pathway in insulin resistance induced by hepatitis C virus core protein.
The hepatitis C virus (HCV) core protein is a component of nucleocapsids and a pathogenic factor for hepatitis C. Several… 
Highly Cited
2006
Highly Cited
2006
Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.
Overexpression of pituitary tumor-transforming 1 (PTTG1) is associated with thyroid cancer. We found elevated PTTG1 levels in the… 
Highly Cited
2006
Highly Cited
2006
Identification of PSME3 as a Novel Serum Tumor Marker for Colorectal Cancer by Combining Two-dimensional Polyacrylamide Gel Electrophoresis with a Strictly Mass Spectrometry-based Approach for Data…
The purpose of this study was to identify and validate novel serological protein biomarkers of human colorectal cancer (CRC… 
Highly Cited
2006
Highly Cited
2006
UV-induced fragmentation of Cajal bodies
The morphology and composition of subnuclear organelles, such as Cajal bodies (CBs), nucleoli, and other nuclear bodies, is… 
Highly Cited
2003
Highly Cited
2003
Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein.
Hepatitis C virus (HCV) core protein plays an important role in the formation of the viral nucleocapsid and a regulatory protein… 
Highly Cited
2000
Highly Cited
2000
Tissue distribution of constitutive proteasomes, immunoproteasomes, and PA28 in rats.
We investigated the expression of standard proteasomes, immunoproteasomes, and their regulators, PA28, and PA700, in rat tissues… 
Highly Cited
1999
Highly Cited
1999
Growth Retardation in Mice Lacking the Proteasome Activator PA28γ*
The proteasome activator PA28 binds to both ends of the central catalytic machine, known as the 20 S proteasome, in opposite… 
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