Skip to search formSkip to main contentSkip to account menu

PS519

Known as: MLN-519, PS 519, PS-519 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Acetylcysteine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
CYTOTOXC AGENTS AND METHODS OF USE
Seemuller, et al. “Proteasome from Thermoplasma acidophilum: A Threonine Protease” Science 268:579-582 (1995). Fenteany, et al… 
2011
2011
Proteasome Inhibitor Reduces Astrocytic iNOS Expression and Functional Deficit after Experimental Intracerebral Hemorrhage in Rats
Intracerebral hemorrhage (ICH) is associated with perihematoma inflammation and edema. We have recently shown cell death and a… 
Review
2007
Review
2007
The ubiquitin-proteasome system and proteasome inhibitors in central nervous system diseases.
The ubiquitin-proteasome system (UPS) displays an important cellular quality control function, by removing abnormal proteins from… 
2006
2006
Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury
Review
2004
Review
2004
[The ubiquitin system for intracellular protein degradation--involvement in human pathologies and therapeutic implications].
The ubiquitin-proteasome pathway has a central role in selective degradation of intracellular proteins. Among the key proteins… 
Review
2003
Review
2003
MLN-519. Millennium/PAION.
Millennium Pharmaceuticals Inc (formerly LeukoSite Inc) and PAION GmbH are developing MLN-519, a ubiquitin/proteasome enzyme… 
2001
2001
Effects of PS-519 combined with thrombolytic therapy in embolic stroke in rat
P67 We evaluated the effect of a proteasome inhibitor (PS-519) which blocks the activation of NF-kB, alone or combination with… 
2000
2000
Proteasome Inhibitor PS 519 Reduces Infarction and Attenuates Leukocyte Infiltration in a Rat Model of Focal Cerebral Ischemia
Background and Purpose —Reperfusion brain injury after cerebral ischemia is associated with a developing inflammatory response at… 
2000
2000
The proteasome inhibitor PS-519 reduces infarction and significantly improves neurological function
  • 2000
  • Corpus ID: 195127455
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)