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PS 15

Known as: PS-15 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Proguanil
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
PS-15 Floating-Gate Based CMUT Sensing Circuit Using Capacitive Feedback Charge Amplifier
This paper describes the use of a floating-gate based capacitive feedback charge amplifier as a receive circuit for CMUT and… 
2006
2006
Relativistic dynamical bistability and adiabatic excitation of strong plasma waves
Adiabatic evolution of the nonlinear resonantly driven dynamical system generic to a variety of plasma physics problems… 
2005
2005
Triazine Inhibits Toxoplasma gondii Tachyzoites In Vitro and In Vivo
ABSTRACT The triazine WR99210 [4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5-trichlorophenoxypropyloxy)-1,3,5 triazine] inhibits… 
1998
1998
Drug Evaluation of Concurrent Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium Complex Infections in a Rat Model
ABSTRACT We present a new experimental model for the simultaneous evaluation of the activities of drugs against Pneumocystis… 
1997
1997
Effects of dual combinations of antifolates with atovaquone or dapsone on nucleotide levels in Plasmodium falciparum.
1997
1997
Effects of folic and folinic acids in the activities of cycloguanil and WR99210 against Plasmodium falciparum in erythrocytic culture.
The in-vitro effects of folinic acid on the antimalarial activities of the triazine antifolates, cycloguanil and WR99210, were… 
1995
1995
In vitro activities of PS-15, a new dihydrofolate reductase inhibitor, and its cyclic metabolite against Mycobacterium avium complex
PS-15, a new dihydrofolate reductase inhibitor, and its cyclic metabolite were evaluated for in vitro activity against 31… 
1994
1994
The activity of PS-15 in combination with sulfamethoxazole.
PS-15 is a novel biguanide folate antagonist that is metabolized in vivo to WR99210, a metabolite that is extremely active in… 
1994
1994
Evaluation of WR250417 (a proguanil analog) for causal prophylactic activity in the Plasmodium cynomolgi-Macaca mulatta model.
The Plasmodium cynomolgi-Macaca mulatta model has been used to test the antimalarial activity of new drugs for both radical cure… 
1993
1993
Anti-Pneumocystis carinii activity of PS-15, a new biguanide folate antagonist
A newly synthesized biguanide inhibitor of dihydrofolate reductase in Plasmodium species was evaluated for its anti-Pneumocystis… 
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