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PRSS8 gene

Known as: PROTEASE, SERINE, 8, PRSS8, protease, serine 8 
This gene is involved in proteolysis in seminal fluid.
National Institutes of Health

Related topics

Related topics

3 relations
HydrolysisPRSS8 protein, humanProteolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin*
The membrane-anchored serine prostasin (CAP1/PRSS8) is essential for barrier acquisition of the interfollicular epidermis and for… 
2014
2014
Increased expression of prostasin contributes to early-onset severe preeclampsia through inhibiting trophoblast invasion
Objective:To investigate the potential role of prostasin, as an invasion suppressor, in the process of trophoblast invasion in… 
2014
2014
The Membrane-anchored Serine Protease Prostasin (CAP1/PRSS8) Supports Epidermal Development and Postnatal Homeostasis Independent of Its Enzymatic Activity*
Background: Prostasin is a membrane-anchored serine protease with essential functions in epithelial development and homeostasis… 
Highly Cited
2013
Highly Cited
2013
Prostasin Is Required for Matriptase Activation in Intestinal Epithelial Cells to Regulate Closure of the Paracellular Pathway*
Background: Matriptase promotes intestinal epithelial barrier formation. Results: Matriptase and prostasin constitute a common… 
Review
2013
Review
2013
Prostasin: An Epithelial Sodium Channel Regulator
Prostasin is a glycophosphatidylinositol-anchored protein which is found in prostate gland, kidney, bronchi, colon, liver, lung… 
Review
2011
Review
2011
Physiological regulation of epithelial sodium channel by proteolysis
Purpose of reviewActivation of epithelial sodium channel (ENaC) by proteolysis appears to be relevant for day-to-day… 
Highly Cited
2010
Highly Cited
2010
Regulation of the Matriptase-Prostasin Cell Surface Proteolytic Cascade by Hepatocyte Growth Factor Activator Inhibitor-1 during Epidermal Differentiation*
Matriptase, a membrane-tethered serine protease, plays essential roles in epidermal differentiation and barrier function, largely… 
2006
2006
Androgen regulation of prostasin gene expression is mediated by sterol‐regulatory element‐binding proteins and SLUG
Prostasin is downregulated in hormone‐refractory prostate cancers (HRPC). The mechanisms by which androgens regulate prostasin… 
Highly Cited
2005
Highly Cited
2005
Identification of Hepatocyte Growth Factor Activator Inhibitor-1B as a Potential Physiological Inhibitor of Prostasin*
Prostasin is a trypsin-like serine protease that is glycosylphosphatidylinositol-anchored to the epithelial cell surface, from… 
2000
2000
Blood–Borne RT–PCR Assay for Prostasin– Specific Transcripts to Identify Circulating Prostate Cells in Cancer Patients
Objective: The aim of this study was to establish the specific detection of prostasin–expressing prostate cells in the blood of… 
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