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PROKR2 gene
Known as:
GPR73L1
, dJ680N4.3
, G PROTEIN-COUPLED RECEPTOR 73-LIKE 1
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This gene is involved in both ligand binding and G protein-coupled receptor signaling.
National Institutes of Health
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Related topics
Related topics
6 relations
G Protein-Coupled Receptor Signaling
Growth Factor Binding
Ligand Binding
PROKR2 protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Kallmann syndrome.
Sachintha Hapugoda
,
Ahmed Abdrabou
Advances in Oto-Rhino-Laryngology
2017
Corpus ID: 823635
This disorder is a form of hypogonadotropic hypogonadism, which is a condition resulting from a lack of production of certain…
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Review
2015
Review
2015
Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment
U. Boehm
,
P. Bouloux
,
+14 authors
Jacques Young
Nature Reviews Endocrinology
2015
Corpus ID: 25979709
Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder caused by the deficient production, secretion or action of…
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Highly Cited
2009
Highly Cited
2009
PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity.
Carine Monnier
,
C. Dodé
,
+5 authors
P. Rondard
Human Molecular Genetics
2009
Corpus ID: 14603996
Kallmann syndrome (KS) combines hypogonadism due to gonadotropin-releasing hormone deficiency, and anosmia or hyposmia, related…
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Review
2008
Review
2008
The Complex Genetics of Kallmann Syndrome: KAL1, FGFR1, FGF8, PROKR2, PROK2, et al.
J. Hardelin
,
C. Dodé
Sexual Development
2008
Corpus ID: 25745850
Kallmann syndrome (KS) combines hypogonadotropic hypogonadism and anosmia. Anosmia is related to the absence or hypoplasia of the…
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Highly Cited
2007
Highly Cited
2007
Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei
H. Prosser
,
A. Bradley
,
J. Chesham
,
F. Ebling
,
M. Hastings
,
E. Maywood
Proceedings of the National Academy of Sciences…
2007
Corpus ID: 26725542
The suprachiasmatic nucleus (SCN), the brain's principal circadian pacemaker, coordinates adaptive daily cycles of behavior and…
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Highly Cited
2006
Highly Cited
2006
Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2.
S. Matsumoto
,
C. Yamazaki
,
+14 authors
Y. Shigeyoshi
Proceedings of the National Academy of Sciences…
2006
Corpus ID: 24929258
Prokineticins, multifunctional secreted proteins, activate two endogenous G protein-coupled receptors PKR1 and PKR2. From in situ…
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Highly Cited
2006
Highly Cited
2006
Kallmann Syndrome: Mutations in the Genes Encoding Prokineticin-2 and Prokineticin Receptor-2
C. Dodé
,
Luis Teixeira
,
+15 authors
J. Hardelin
PLoS Genetics
2006
Corpus ID: 13612724
Kallmann syndrome combines anosmia, related to defective olfactory bulb morphogenesis, and hypogonadism due to gonadotropin…
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Highly Cited
2006
Highly Cited
2006
Sensitization of Transient Receptor Potential Vanilloid 1 by the Prokineticin Receptor Agonist Bv8
V. Vellani
,
M. Colucci
,
+4 authors
P. McNaughton
Journal of Neuroscience
2006
Corpus ID: 16762019
Small mammalian proteins called the prokineticins [prokineticin 1 (PK1) and PK2] and two corresponding G-protein-coupled…
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Highly Cited
2002
Highly Cited
2002
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
Michelle Y. Cheng
,
C. Bullock
,
+6 authors
Q. Zhou
Nature
2002
Corpus ID: 1357536
The suprachiasmatic nucleus (SCN) controls the circadian rhythm of physiological and behavioural processes in mammals. Here we…
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Highly Cited
2001
Highly Cited
2001
Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle.
Ming Li
,
C. Bullock
,
D. Knauer
,
Frederick J. Ehlert
,
Qun-Yong Zhou
Molecular Pharmacology
2001
Corpus ID: 1597745
The motility of gastrointestinal tract is regulated by classical neurotransmitters, neuropeptides, and humoral agents. Two novel…
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