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PRKCI wt Allele

Known as: PKCI, DXS1179E, nPKC-iota 
Human PRKCI wild-type allele is located in the vicinity of 3q26.3 and is approximately 84 kb in length. This allele, which encodes protein kinase C… 
National Institutes of Health

Related topics

Related topics

10 relations
3q26.3Cell Surface ExtensionsCytoskeletal ModelingInsulin/Insulin Receptor Signaling Pathway

Broader (1)

PRKCI gene

Papers overview

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2010
2010
Attenuation of renal ischemia–reperfusion injury by postconditioning involves adenosine receptor and protein kinase C activation
Significant organ injury occurs after transplantation and reflow (i.e., reperfusion injury). Postconditioning (PoC), consisting… 
Highly Cited
2004
Highly Cited
2004
Role of mPKCI, a novel mu-opioid receptor interactive protein, in receptor desensitization, phosphorylation, and morphine-induced analgesia.
The human mu-opioid receptor (HmuOR) is a G-protein coupled receptor that mediates analgesia, euphoria and other important… 
Highly Cited
2003
Highly Cited
2003
Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis
PKC-interacting protein (PKCI), also designated histidine triad nucleotide-binding protein 1, belongs to the histidine triad (HIT… 
Highly Cited
2002
Highly Cited
2002
Stability of a PKCI-1-related mRNA is controlled by the splicing factor ASF/SF2: a novel function for SR proteins.
Pre-mRNA splicing is a widely used regulatory mechanism for controlling gene expression, and a family of conserved proteins, SR… 
Highly Cited
2001
Highly Cited
2001
Inhibition of potentially anti-apoptotic proteins by antisense protein kinase C-alpha (Isis 3521) and antisense bcl-2 (G3139) phosphorothioate oligodeoxynucleotides: relationship to the decreased…
Isis 3521 and G3139 are 20- and 18-mer phosphorothioate oligonucleotides, respectively, targeted to the protein kinase C (PKC… 
Highly Cited
2001
Highly Cited
2001
Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu.
We have investigated the effects of various fatty acids (FAs) on integrin-mediated MDA-MB-435 breast carcinoma cell adhesion to… 
Highly Cited
2000
Highly Cited
2000
Wpkci, encoding an altered form of PKCI, is conserved widely on the avian W chromosome and expressed in early female embryos: implication of its role in female sex determination.
Two W chromosome-linked cDNA clones, p5fm2 and p5fm3, were obtained from a subtracted (female minus male) cDNA library prepared… 
Highly Cited
1999
Highly Cited
1999
Suppression of Microphthalmia Transcriptional Activity by Its Association with Protein Kinase C-interacting Protein 1 in Mast Cells*
Microphthalmia (mi) is a transcription factor that plays a major role in the regulation of growth and function in mast cells and… 
Highly Cited
1995
Highly Cited
1995
Tetanically induced LTP involves a similar increase in the AMPA and NMDA receptor components of the excitatory postsynaptic current: investigations of the involvement of mGlu receptors
Whole-cell patch-clamp recordings of evoked excitatory postsynaptic currents (EPSCs) were made from granule cells of the rat… 
Highly Cited
1990
Highly Cited
1990
Arachidonic acid modulates hippocampal calcium current via protein kinase C and oxygen radicals
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