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PRKACA gene
Known as:
protein kinase cAMP-activated catalytic subunit alpha
, PRKACA
, PKACa
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This gene is involved in the regulation of diverse cell processes including cell growth, proliferation, differentiation and motility.
National Institutes of Health
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Related topics
Related topics
6 relations
PRKACA protein, human
PRKACA wt Allele
Phosphorylation
Serine/Threonine Phosphorylation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract 4142: Conformational dynamics of the chimeric kinase DNAJB1-PRKACA, the driver for fibrolamellar hepatocellular carcinoma
Michael D Tomasini
,
Y. Wang
,
+5 authors
S. Simon
Tumor Biology
2018
Corpus ID: 81615608
In fibrolamellar hepatocellular carcinoma (FLC) there is a single common genetic alteration in all tumors: A deletion in one copy…
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2017
2017
Identification and Characterization of Novel PRKACA Mutations in Adrenocortical Tumors.
Rajani Maharjan
,
Tobias Åkerström
,
S. Backman
,
P. Hellman
,
P. Björklund
2017
Corpus ID: 90180456
2016
2016
Une approche moléculaire pour mieux comprendre l'infertilité chez la vache laitière
Laurianne Gagnon-Duval
2016
Corpus ID: 75493386
Over the last fifty or more years, genetic selection has been employed to improve milk production in dairy cattle. This selection…
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2013
2013
Abstract P5-08-01: Systematic interrogation of resistance to HER2-directed therapy identifies a survival pathway activated by PRKACA and PIM1
S. Moody
,
Anna C. Schinzel
,
+8 authors
W. Hahn
2013
Corpus ID: 72222880
Amplification and/or overexpression of the receptor tyrosine kinase HER2 occurs in 20-25% of breast cancers, and is associated…
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2011
2011
Overcoming Resistance to Trastuzumab in HER2-Amplified Breast Cancers
S. Moody
2011
Corpus ID: 68803741
Abstract : The receptor tyrosin kinase HER2 is amplified and/or overexpressed in 25-30% of all breast cancers. Blockade of HER2…
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2008
2008
Short title: Regulation of CDC25B in the first mitotic cell cycle Summary sentence: PRKACA can inhibit G2/M transition by regulating CDC25B negatively in mouse fertilized eggs.
Cheng Cui
,
Hongmei Zhao
,
+5 authors
Bing‐zhi Yu
2008
Corpus ID: 88460094
Protein kinase A (PRKACA) has been documented as a pivotal regulator in meiosis and mitosis arrest. Although our previous work…
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