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PRKACA gene

Known as: protein kinase cAMP-activated catalytic subunit alpha, PRKACA, PKACa 
This gene is involved in the regulation of diverse cell processes including cell growth, proliferation, differentiation and motility.
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Our appreciation of the scope and influence of second messenger signaling has its origins in pioneering work on the cAMP… Expand
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Highly Cited
2015
Highly Cited
2015
The incidence of biliary tract cancer (BTC), including intrahepatic (ICC) and extrahepatic (ECC) cholangiocarcinoma and… Expand
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Highly Cited
2015
Highly Cited
2015
Fibrolamellar carcinoma is a distinct subtype of hepatocellular carcinoma that predominantly affects young patients without… Expand
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Highly Cited
2014
Highly Cited
2014
Adrenal Cushing’s syndrome is caused by excess production of glucocorticoid from adrenocortical tumors and hyperplasias, which… Expand
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Highly Cited
2014
Highly Cited
2014
Oncogenic Suspect Exposed It can be difficult logistically to study the genomics of rare variants of common cancers. Nevertheless… Expand
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Highly Cited
2014
Highly Cited
2014
Adrenal tumors autonomously producing cortisol cause Cushing's syndrome. We performed exome sequencing of 25 tumor-normal pairs… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Corticotropin-independent Cushing's syndrome is caused by tumors or hyperplasia of the adrenal cortex. The molecular… Expand
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Highly Cited
2014
Highly Cited
2014
The authors report that a gain of function in the catalytic subunit beta of the cyclic AMP–dependent protein kinase (protein… Expand
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Highly Cited
2009
Highly Cited
2009
show potent and selective antiproliferative properties against human umbilical vein endothelial cells (HUVECs) spurred a surge of… Expand
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Highly Cited
2007
Highly Cited
2007
FOXA1 (14q21.1) FOXA2, FOXA3, RXRA, PMA, MSA, Ie86, INS1, NR0B2, DHT, POU5F1, FOXD3, GR, PRKACA, LRP5, ER GCG, TCF1, TFF1, INS1… Expand
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