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Background: H2O2 oxidizes peroxiredoxins (Prxs) to sulfenic acid intermediates which form disulfides or become hyperoxidized… Expand Hydrogen peroxide is widely viewed as the main second messenger in redox signaling, and it has been proposed that deactivation of… Expand Peroxiredoxins (Prx) are thiol peroxidases that exhibit exceptionally high reactivity toward peroxides, but the chemical basis… Expand Multiple lines of evidence indicate that the platinum-containing cancer drugs enter cells, are distributed to various subcellular… Expand The proteins from the thioredoxin family are crucial actors in redox signaling and the cellular response to oxidative stress. The… Expand Thioredoxin reductase (TrxR) is a key selenoprotein antioxidant enzyme and a potential target for anti-cancer drugs. One potent… Expand Secondary metabolites are a diverse set of plant compounds believed to have numerous functions in plant–environment interactions… Expand The mitochondrial protein SP-22 has recently been reported to be a member of the thioredoxin-dependent peroxide reductase family… Expand SP-22 is a mitochondrial antioxidant protein in bovine adrenal cortex. The protein is homologous to thioredoxin peroxidase and… Expand A highly immunogenic epitope from a conserved COOH-terminal region of the human immunodeficiency virus (HIV) gp120 envelope… Expand