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PRDM16 gene

Known as: transcription factor MEL1, KIAA1675, PR domain 16 
This gene plays a role in both transcriptional regulation and adipocyte differentiation.
National Institutes of Health

Related topics

Related topics

8 relations
Cell Differentiation processCell RespirationHomo sapiensPR Domain Zinc Finger Protein 16

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PRDM16 wt Allele

Papers overview

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2010
2010
PPARalpha does not suppress muscle-associated gene expression in brown adipocytes but does influence expression of factors that fingerprint the brown adipocyte.
2008
2008
Cryptic and partial deletions of PRDM16 and RUNX1 without t(1;21)(p36;q22) and/or RUNX1–PRDM16 fusion in a case of progressive chronic myeloid leukemia: A complex chromosomal rearrangement of…
Chronic myeloid leukemia (CML) is a myeloproliferative disorder characterized by the presence in leukemic stem cells of the… 
2004
2004
Aberrant expression of the MEL 1 S gene identified in association with hypomethylation in adult T-cell leukemia cells
DNA methylation plays critical roles in the development and differentiation of mammalian cells, and its dysregulation has been… 
Highly Cited
2000
Highly Cited
2000
Physiological studies in aerobic batch cultivations of Saccharomyces cerevisiae strains harboring the MEL1 gene
Physiological studies of Saccharomyces cerevisiae strains harboring the MEL1 gene were carried out in aerobic batch cultivations… 
1996
1996
Identification of the alpha-galactosidase MEL genes in some populations of Saccharomyces cerevisiae: a new gene MEL11.
In this report we mapped a new MEL11 gene and summarize our population studies of the alpha-galactosidase MEL genes of S… 
1995
1995
Characterization of genetically transformed Saccharomyces cerevisiae baker's yeasts able to metabolize melibiose
Three transformant (Mel+) Saccharomyces cerevisiae baker's yeast strains, CT-Mel, VS-Mel, and DADI-Mel, have been characterized… 
1991
1991
Mutations of the alpha-galactosidase signal peptide which greatly enhance secretion of heterologous proteins by yeast.
1989
1989
The construction of recombinant industrial yeasts free of bacterial sequences by directed gene replacement into a nonessential region of the genome.
Highly Cited
1985
Highly Cited
1985
The nucleotide sequence of the yeast MEL1 gene.
The complete nucleotide sequence of the MEL1 gene of the yeast, Saccharomyces cerevisiae, encoding alpha-galactosidase was… 
Highly Cited
1984
Highly Cited
1984
Regulation of basal and induced levels of the MEL1 transcript in Saccharomyces cerevisiae
The MEL1 gene in Saccharomyces cerevisiae is required for the production of alpha-galactosidase and for the catabolism of… 
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