PRDM16 gene

Known as: transcription factor MEL1, KIAA1675, PR domain 16 
This gene plays a role in both transcriptional regulation and adipocyte differentiation.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
A clear relationship exists between visceral obesity and type 2 diabetes, whereas subcutaneous obesity is comparatively benign… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2014
Highly Cited
2014
Prdm16 is a transcription factor that regulates the thermogenic gene program in brown and beige adipocytes. However, whether… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Brown adipose tissue dissipates energy through heat and functions as a defense against cold and obesity. PPARγ ligands have been… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Heterochromatin serves important functions, protecting genome integrity and stabilizing gene expression programs. Although the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Fetal liver and adult bone marrow hematopoietic stem cells (HSCs) renew or differentiate into committed progenitors to generate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Peroxisome proliferator activated receptor α (PPARα) is a distinctive marker of the brown fat phenotype that has been proposed to… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
To better understand the mechanisms that regulate stem cell identity and function, we sought to identify genes that are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Transcriptional cofactors are essential to the regulation of transforming growth factor beta (TGFbeta) superfamily signaling and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Brown adipose cells are specialized to dissipate chemical energy in the form of heat, as a physiological defence against cold and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2009
2009
Both brown and white adipocytes were previously considered to be derived from the same precursor cell, despite being… (More)
Is this relevant?