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PRDM1 gene

Known as: PRDIBF1, PRDM1, PRDI-BF1 
This gene is involved in repression of transcription. It plays a role in the formation of pre-plasma memory B cells and immunoglobulin-secreting… 
National Institutes of Health

Related topics

Related topics

4 relations
PR Domain Zinc Finger Protein 1Transcriptional RegulationTranscriptional Repression

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PRDM1 wt Allele

Papers overview

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2017
2017
Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival
2017
2017
Identification of tonsillar CD4+CD25-LAG3+ T cells as naturally occurring IL-10-producing regulatory T cells in human lymphoid tissue.
2015
2015
PRDM1 expression via human parvovirus B19 infection plays a role in the pathogenesis of Hashimoto thyroiditis.
2014
2014
Transcriptional repression of plasma cell differentiation is orchestrated by aberrant over‐expression of the ETS factor SPIB in Waldenström macroglobulinaemia
In Waldenström macroglobulinaemia (WM), the mechanism(s) responsible for repression of B‐cell differentiation remains unknown. We… 
Review
2013
Review
2013
II. Therapy of DLBCL based on genomics
The activated B-cell-like (ABC) and germinal centre B-cell-like (GCB) subtypes of diffuse large B-cell lymphoma (DLBCL) were… 
2011
2011
Germline competency of parthenogenetic embryonic stem cells from immature oocytes of adult mouse ovary.
Parthenogenetic embryonic stem cells (pESCs) have been generated in several mammalian species from parthenogenetic embryos that… 
2010
2010
Prdm1 (Blimp-1) and the Expression of Fast and Slow Myosin Heavy Chain Isoforms during Avian Myogenesis In Vitro
Background Multiple types of fast and slow skeletal muscle fibers form during early embryogenesis in vertebrates. In zebrafish… 
Highly Cited
2008
Highly Cited
2008
Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma
Primary lymphomas of the CNS (PCNSLs) show molecular features of the late germinal center exit B-cell phenotype and are impaired… 
Highly Cited
2008
Highly Cited
2008
Characterization of 6q deletions in mature B cell lymphomas and childhood acute lymphoblastic leukemia
The study was undertaken with the aim to outline deletion patterns involving the long arm of chromosome 6, a common abnormality… 
Highly Cited
1996
Highly Cited
1996
The B-lymphocyte maturation promoting transcription factor BLIMP1/PRDI-BF1 maps to D6S447 on human chromosome 6q21-q22.1 and the syntenic region of mouse chromosome 10.
The human PRDI-BF1 or BLIMP1 gene and its mouse homolog Blimp1 are members of the recently realized PR domain family that… 
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