PR Domain Zinc Finger Protein 1

Known as: B-Lymphocyte-Induced Maturation Protein 1, BLIMP-1, PRDM1 
PR domain zinc finger protein 1 (825 aa, ~92 kDa) is encoded by the human PRDM1 gene. This protein is involved in the negative regulation of gene… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Effective B cell-mediated immunity and antibody responses often require help from CD4+ T cells. It is thought that a distinct CD4… (More)
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Highly Cited
2009
Highly Cited
2009
During acute infections, a small population of effector CD8(+) T cells evades terminal differentiation and survives as long-lived… (More)
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Highly Cited
2008
Highly Cited
2008
Specification of germ cell fate is fundamental in development. With a highly representative single-cell microarray and rigorous… (More)
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Highly Cited
2005
Highly Cited
2005
Blimp1, a zinc-finger containing DNA-binding transcriptional repressor, functions as a master regulator of B cell terminal… (More)
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Highly Cited
2004
Highly Cited
2004
The differentiation of B cells into immunoglobulin-secreting plasma cells is controlled by two transcription factors, Blimp-1 and… (More)
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Highly Cited
2004
Highly Cited
2004
IL-21 is a type I cytokine whose receptor is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1… (More)
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Highly Cited
2003
Highly Cited
2003
Blimp-1 is a transcriptional repressor able to drive the terminal differentiation of B cells into Ig-secreting plasma cells. We… (More)
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Highly Cited
2002
Highly Cited
2002
Blimp-1, a transcriptional repressor, drives the terminal differentiation of B cells to plasma cells. Using DNA microarrays, we… (More)
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Highly Cited
2000
Highly Cited
2000
BCL-6, a transcriptional repressor frequently translocated in lymphomas, regulates germinal center B cell differentiation and… (More)
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Highly Cited
1994
Highly Cited
1994
We describe a novel gene, Blimp-1 (for B lymphocyte-induced maturation protein), transcripts of which are rapidly induced during… (More)
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