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POU2F1 gene

Known as: POU2F1, POU Domain, Class 2, Transcription Factor 1 Gene, OCT1 
This gene plays a role in transcriptional activation and modulates immunoglobulin activity.
National Institutes of Health

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Cell Differentiation processHomo sapiensImmune responsePOU2F1 protein, human

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POU2F1 wt Allele

Papers overview

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2019
2019
LncRNA SND1-IT1 accelerates the proliferation and migration of osteosarcoma via sponging miRNA-665 to upregulate POU2F1.
OBJECTIVE To clarify the role of long non-coding RNA (lncRNA) SND1-IT1 in accelerating the proliferative and migratory abilities… 
2015
2015
Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1
The organic cation transporter OCT1 (SLC22A1) mediates the uptake of vitamin B1, cationic drugs, and xenobiotics into hepatocytes… 
2014
2014
Genetic association of IDE, POU2F1, PON1, IL1α and IL1β with type 2 diabetes in Pakistani population
A number of genes are known to be involved in glucose homeostasis. Mutations and polymorphisms in candidate genes may effect… 
2011
2011
Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).
2010
2010
Calcium kidney stones are associated with a haplotype of the calcium-sensing receptor gene regulatory region.
BACKGROUND Calcium-sensing receptor gene (CaSR) is a candidate to explain susceptibility to calcium kidney stones. Thus, we… 
2010
2010
Association of the POU class 2 homeobox 1 gene (POU2F1) with susceptibility to Type 2 diabetes in Chinese populations
Diabet. Med. 27, 1443–1449 (2010) 
2009
2009
Inhibition of AR‐mediated transcription by binding of Oct1 to a motif enriched in AR‐occupied regions
The androgen receptor (AR) plays roles in prostate development and cancer (PCa). In response to androgens, the AR binds to… 
2008
2008
Mechanisms of SHP‐1 P2 promoter regulation in hematopoietic cells and its silencing in HTLV‐1‐transformed T cells
The Src homology‐2‐containing protein‐tyrosine phosphatase 1 (SHP‐1), is a negative regulator of cell signaling. It is also… 
1995
1995
Transcription factor Oct1 binds to the AT-rich segment of the simian virus 40 replication origin
A cellular protein that binds to the AT-rich late segment of the simian virus 40 (SV40) origin of replication has been identified… 
Highly Cited
1990
Highly Cited
1990
Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of…
Several distinct octamer-binding transcription factors (OTFs) interact with the sequence ATTTGCAT (the octamer motif), which acts… 
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