Skip to search formSkip to main contentSkip to account menu

POU2F1 protein, human

Known as: Oct-1, NF-A1, OTF-1 
POU domain, class 2, transcription factor 1 (743 aa, ~76 kDa) is encoded by the human POU2F1 gene. This protein plays a role in the regulation of… 
National Institutes of Health

Related topics

Related topics

14 relations
Androgen Receptor Regulation PathwayCell NucleusDNA-Binding ProteinsGenes, Regulator

Broader (1)

octamer transcription factor OTF-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Activation of the transcription factor Oct-1 in response to DNA damage.
Mammalian cells exhibit complex cellular responses to genotoxic stress, including cell cycle checkpoint, DNA repair, and… 
2000
2000
Transcriptional Activation of the Human Hematopoietic Prostaglandin D Synthase Gene in Megakaryoblastic Cells
The human hematopoietic prostaglandin D synthase (H-PGDS) gene is highly expressed in human megakaryoblastic cells, in which… 
Highly Cited
1999
Highly Cited
1999
The Glucocorticoid Receptor Is Tethered to DNA-bound Oct-1 at the Mouse Gonadotropin-releasing Hormone Distal Negative Glucocorticoid Response Element*
An element required for glucocorticoid repression of mouse gonadotropin-releasing hormone (GnRH) gene transcription, the distal… 
Highly Cited
1998
Highly Cited
1998
Interaction of Oct‐1 and automodification domain of poly(ADP‐ribose) synthetase
Highly Cited
1997
Highly Cited
1997
Using altered specificity Oct‐1 and Oct‐2 mutants to analyze the regulation of immunoglobulin gene transcription
Oct‐1 and Oct‐2 represent the prototypical example of related transcription factors with identical DNA recognition properties… 
Highly Cited
1996
Highly Cited
1996
The transcription factors Sp1 and Oct-1 interact physically to regulate human U2 snRNA gene expression.
The expression of human small nuclear U2 RNA genes is controlled by the proximal sequence element (PSE), which determines the… 
Highly Cited
1995
Highly Cited
1995
The POU homeodomain transcription factor Oct-1 is essential for activity of the gonadotropin-releasing hormone neuron-specific enhancer
The mechanisms of specification of gene expression in a complex tissue such as the brain remain poorly understood. To provide a… 
1993
1993
Convergent regulation of NF-IL6 and Oct-1 synthesis by interleukin-6 and retinoic acid signaling in embryonal carcinoma cells
The nuclear signaling by the pleiotropic cytokine interleukin-6 (IL-6) has been investigated in human embryonal carcinoma cells… 
Highly Cited
1991
Highly Cited
1991
Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40.
After antigenic stimulation of T lymphocytes, genes essential for proliferation and immune function, such as the interleukin-2… 
Highly Cited
1991
Highly Cited
1991
Repression of the human papillomavirus type 18 enhancer by the cellular transcription factor Oct-1
The role of cellular factors involved in the transcriptional regulation of the cancer-associated human papillomavirus type 18… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)