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POU2F1 protein, human

Known as: Oct-1, NF-A1, OTF-1 
POU domain, class 2, transcription factor 1 (743 aa, ~76 kDa) is encoded by the human POU2F1 gene. This protein plays a role in the regulation of… 
National Institutes of Health

Related topics

Related topics

14 relations
Androgen Receptor Regulation PathwayCell NucleusDNA-Binding ProteinsGenes, Regulator

Broader (1)

octamer transcription factor OTF-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
POU Homeodomain Protein Oct-1 Functions as a Sensor for Cyclic AMP*
Cyclic AMP is a fundamentally important second messenger for numerous peptide hormones and neurotransmitters that control gene… 
2007
2007
Involvement of the ubiquitous Oct-1 transcription factor in hormonal induction of beta-casein gene expression.
Transcription of the milk protein beta-casein gene is induced by the lactogenic hormones Prl (prolactin) and glucocorticoids… 
Highly Cited
2004
Highly Cited
2004
TALE Homeodomain Proteins Regulate Gonadotropin-releasing Hormone Gene Expression Independently and via Interactions with Oct-1*
Gonadotropin-releasing hormone (GnRH) is the central regulator of reproductive function. Expression of the GnRH gene is confined… 
2001
2001
Octamer binding protein-1 is involved in inhibition of inducible nitric oxide synthase expression by exogenous nitric oxide in murine liver cells.
Nitric oxide (NO) has diverse effects on immune responses and hepatic functions. In BNL CL.2 cells, the murine embryonic liver… 
1999
1999
Retinoblastoma protein expression leads to reduced Oct-1 DNA binding activity and enhances interleukin-8 expression.
Tumor cell lines with a defective retinoblastoma gene are unable to transcribe the HLA class II genes in response to IFN-gamma… 
1993
1993
Convergent regulation of NF-IL6 and Oct-1 synthesis by interleukin-6 and retinoic acid signaling in embryonal carcinoma cells
The nuclear signaling by the pleiotropic cytokine interleukin-6 (IL-6) has been investigated in human embryonal carcinoma cells… 
1993
1993
The adenovirus DNA binding protein effects the kinetics of DNA replication by a mechanism distinct from NFI or Oct-1.
Initiation of adenovirus DNA replication in vitro minimally requires the viral TP-DNA template and the precursor terminal protein… 
Highly Cited
1991
Highly Cited
1991
Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40.
After antigenic stimulation of T lymphocytes, genes essential for proliferation and immune function, such as the interleukin-2… 
Highly Cited
1991
Highly Cited
1991
Repression of the human papillomavirus type 18 enhancer by the cellular transcription factor Oct-1
The role of cellular factors involved in the transcriptional regulation of the cancer-associated human papillomavirus type 18… 
1990
1990
The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes
All immunoglobulin genes contain a conserved octanucleotide promoter element, ATGCAAAT, which has been shown to be required for… 
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