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Interaction of lamins with chromatin and transcription factors regulate transcription. Oct-1 has previously been shown to… Expand Two phenotypes exist in the human population with regard to expression of lactase in adults. Lactase non-persistence (adult-type… Expand The human UDP glucuronosyltransferase, UGT2B7, is expressed in the liver and gastrointestinal tract, where it catalyzes the… Expand We isolated several clones from a matchmaker two‐hybrid system human lymphocyte cDNA library using an automodification domain of… Expand In HeLa cells, RNA polymerase II mediated transcription is severely inhibited by poliovirus infection. Both basal and activated… Expand The expression of human small nuclear U2 RNA genes is controlled by the proximal sequence element (PSE), which determines the… Expand The mechanisms of specification of gene expression in a complex tissue such as the brain remain poorly understood. To provide a… Expand DNA-dependent and DNA-independent associations of DNA-binding proteins are important in transcriptional regulation. The analysis… Expand The promoter specificity of transcriptional activators is generally thought to be conferred by the specificity of the DNA-binding… Expand Induction of transcription of the immediate-early (IE) genes of herpes simplex virus involves the assembly of a DNA-binding… Expand