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POU Domain

The POU domain is a bipartite DNA binding domain recognized originally as a shared structural motif in the Pit-1, Oct-1/Oct-2, and Unc-86… 
National Institutes of Health

Related topics

Related topics

5 relations
POU2F1 protein, humanPOU2F2 protein, humanPOU3F2 protein, humanPOU5F1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Axotomy-induced early down-regulation of POU-IV class transcription factors Brn-3a and Brn-3b in retinal ganglion cells
It has been proposed that neurons being exposed to proapoptotic stimuli undergo dedifferentiation, a process that can either… 
2004
2004
Developmental expression of the POU domain transcription factor Brn‐3b (Pou4f2) in the lateral line and visual system of zebrafish
Members of the class IV POU domain transcription factors are important regulators of neural development. In mouse, Brn‐3b (Pou4f2… 
2000
2000
Complex Interactions between Epidermal POU Domain and Activator Protein 1 Transcription Factors Regulate the Expression of the Profilaggrin Gene in Normal Human Epidermal Keratinocytes*
The human profilaggrin gene is expressed in the granular layer during the late stages of the epidermal differentiation. The… 
Review
1997
Review
1997
POU domain transcription factors in embryonic development
One of the families of transcription factors implicated in developmental control of gene expression is that of the POU domain… 
1997
1997
Characterization of Skn-1a/i POU Domain Factors and Linkage to Papillomavirus Gene Expression*
Tissue-restricted POU domain transcription factors, which bind octamer or octamer-like gene sequences, play roles in cellular… 
Highly Cited
1996
Highly Cited
1996
Regulation of Human Involucrin Promoter Activity by POU Domain Proteins*
POU domain transcription factors are expressed in the epidermis and are thought to be important regulators of keratinocyte gene… 
Highly Cited
1995
Highly Cited
1995
PU box-binding transcription factors and a POU domain protein cooperate in the Epstein-Barr virus (EBV) nuclear antigen 2-induced transactivation of the EBV latent membrane protein 1 promoter.
Expression of the Epstein-Barr virus (EBV) latent membrane protein (LMP1) is regulated by virus- and host cell-specific factors… 
1994
1994
A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues.
POU domain genes constitute a family of transcription factors that exhibit distinct temporal and spatial patterns of expression… 
1992
1992
Biochemical characterization of the Oct-2 POU domain with implications for bipartite DNA recognition.
B-cell specific regulation of immunoglobulin gene expression provides a model for the interaction of promoter and enhancer… 
1992
1992
POU domain transcription factors from different subclasses stimulate adenovirus DNA replication.
POU domain proteins constitute a family of eukaryotic transcription factors that exert critical functions during development… 
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