POU Domain

The POU domain is a bipartite DNA binding domain recognized originally as a shared structural motif in the Pit-1, Oct-1/Oct-2, and Unc-86… (More)
National Institutes of Health

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Highly Cited
2003
Highly Cited
2003
Axonal selection of synaptic partners is generally believed to determine wiring specificity in the nervous system. However, we… (More)
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Highly Cited
2003
Highly Cited
2003
Homologous recombination applied to mouse embryonic stem (ES) cells has revolutionized the study of gene function in mammals… (More)
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Highly Cited
2001
Highly Cited
2001
During retinogenesis, the Xenopus basic helix-loop-helix transcription factor Xath5 has been shown to promote a ganglion cell… (More)
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Highly Cited
1997
Highly Cited
1997
Pit-1, a member of the POU domain family of transcription factors, characterized by a bipartite DNA-binding domain, serves… (More)
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Highly Cited
1996
Highly Cited
1996
The three members of the Brn-3 family of POU domain transcription factors are found in highly restricted sets of central nervous… (More)
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Highly Cited
1995
Highly Cited
1995
Deafness with fixation of the stapes (DFN3) is the most frequent X-linked form of hearing impairment. The underlying gene has… (More)
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Highly Cited
1993
Highly Cited
1993
A search for POU domain transcription factors in human retina cDNA has led to the identification of Brn-3b, a class IV POU domain… (More)
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Highly Cited
1992
Highly Cited
1992
The POU domain is a conserved DNA binding region of approximately 160 amino acids present in a family of eukaryotic transcription… (More)
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1992
1992
Four mouse POU domain genomic DNA clones--Brain-1, Brain-2, Brain-4, and Scip--and Brain-2 cDNA, which are expressed in adult… (More)
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Highly Cited
1990
Highly Cited
1990
MEMBERS of a family of murine octamer-binding proteins inter-act specifically with the octamer motif, a transcription regulatory… (More)
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