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PNU 166196

Known as: PNU-166196, PNU166196 
National Institutes of Health

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brostallicin

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2003
2003
Phase I and Pharmacokinetic Study of Brostallicin ( PNU-166196 ) , a New DNA Minor-Groove Binder , Administered Intravenously Every 3 Weeks to Adult Patients with Metastatic Cancer 1
Purpose: Brostallicin (PNU-166196) is a cytotoxic agent that binds to the minor groove of DNA with significant antitumor activity… 
2001
2001
Brostallicin (PNU-166196), a DNA minor groove binder characterized by alpha-halogenoacrylamide moiety linked to tetrapyrrole frame, shows unusual mechanistic features.