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PNPT1 wt Allele

Known as: DKFZp762K1914, old-35, OLD35 
Human PNPT1 wild-type allele is located in the vicinity of 2p15 and is approximately 60 kb in length. This allele, which encodes polyribonucleotide… 
National Institutes of Health

Related topics

Related topics

6 relations
2p15PhosphorylationRNA DegradationRNA Processing

Broader (1)

PNPT1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Mammalian Polynucleotide Phosphorylase Is an Intermembrane Space RNase That Maintains Mitochondrial Homeostasis
ABSTRACT We recently identified polynucleotide phosphorylase (PNPase) as a potential binding partner for the TCL1 oncoprotein… 
Highly Cited
2003
Highly Cited
2003
Quality control of ribosomal RNA mediated by polynucleotide phosphorylase and RNase R
Despite their overall accuracy, errors in macromolecular processes, such as rRNA synthesis and ribosome assembly, inevitably… 
Highly Cited
2002
Highly Cited
2002
Polynucleotide phosphorylase is a global regulator of virulence and persistency in Salmonella enterica
For many pathogens, the ability to regulate their replication in host cells is a key element in establishing persistency. Here… 
Highly Cited
2001
Highly Cited
2001
Polynucleotide Phosphorylase Functions as Both an Exonuclease and a Poly(A) Polymerase in Spinach Chloroplasts
ABSTRACT The molecular mechanism of mRNA degradation in the chloroplast consists of sequential events including endonucleolytic… 
Highly Cited
2000
Highly Cited
2000
Action of RNase II and Polynucleotide Phosphorylase against RNAs Containing Stem-Loops of Defined Structure
ABSTRACT The 3′→5′ exoribonucleases, RNase II and polynucleotide phosphorylase (PNPase), play an essential role in degrading… 
Highly Cited
1998
Highly Cited
1998
The endoribonucleolytic N-terminal half of Escherichia coli RNase E is evolutionarily conserved in Synechocystis sp. and other bacteria but not the C-terminal half, which is sufficient for…
Escherichia coli RNase E, an essential single-stranded specific endoribonuclease, is required for both ribosomal RNA processing… 
Highly Cited
1996
Highly Cited
1996
Polynucleotide phosphorylase is necessary for competence development in Bacillus subtilis
comR (pnpA) is a newly identified gene in Bacillus subtilis that is necessary for the expression of late competence genes… 
Highly Cited
1996
Highly Cited
1996
PNPase modulates RNase II expression in Escherichia coli: implications for mRNA decay and cell metabolism
PNPase and RNase II are the key regulatory exo‐nucleases controlling mRNA decay in Escherichia coli The rnb transcripts were… 
Highly Cited
1994
Highly Cited
1994
Copurification of E. coli RNAase E and PNPase: Evidence for a specific association between two enzymes important in RNA processing and degradation
Highly Cited
1986
Highly Cited
1986
Polynucleotide phosphorylase and ribonuclease II are required for cell viability and mRNA turnover in Escherichia coli K-12.
The isolation of a temperature-sensitive allele of RNase II (rnb) by in vitro mutagenesis has permitted the demonstration that… 
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