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PNPT1 gene

Known as: old-35, POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, OLD35 
This gene is involved in the processing of mRNA.
National Institutes of Health

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PNPT1 wt Allele
PhosphorylationPolyribonucleotide NucleotidyltransferasePolyribonucleotide Nucleotidyltransferase 1, MitochondrialRNA Degradation

Papers overview

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2015
2015
Direct observation of processive exoribonuclease motion using optical tweezers
Significance Bacteria regulate the synthesis and degradation of RNA molecules to ensure timely and robust responses to an ever… 
Highly Cited
2009
Highly Cited
2009
Polyadenylation in Arabidopsis and Chlamydomonas organelles: the input of nucleotidyltransferases, poly(A) polymerases and polynucleotide phosphorylase.
The polyadenylation-stimulated RNA degradation pathway takes place in plant and algal organelles, yet the identities of the… 
2009
2009
The poly(A)-dependent degradation pathway of rpsO mRNA is primarily mediated by RNase R.
Polyadenylation is an important factor controlling RNA degradation and RNA quality control mechanisms. In this report we… 
2007
2007
hTERT-targeted E. coli purine nucleoside phosphorylase gene/6-methylpurine deoxyribose therapy for pancreatic cancer.
BACKGROUND Pancreatic cancer is one of the most common tumors and has a 5-year survival for all stages of less than 5%. Most… 
Review
2004
Review
2004
Cooperation of endo- and exoribonucleases in chloroplast mRNA turnover.
2002
2002
cDNA cloning confirms the polyadenylation of RNA decay intermediates in Streptomyces coelicolor.
In Escherichia coli the poly(A) tails of messenger and rRNAs are a major determinant of RNA stability. These tails are formed… 
1999
1999
Preferential degradation of polyadenylated and polyuridinylated RNAs by the bacterial exoribonuclease polynucleotide phosphorylase.
Polyadenylation of mRNA has been shown to target the RNA molecule for rapid exonucleolytic degradation in bacteria. To elucidate… 
1998
1998
Polynucleotide Phosphorylase Is a Component of a Novel Plant Poly(A) Polymerase*
We have isolated cDNA clones encoding a novel RNA-binding protein that is a component of a multisubunit poly(A) polymerase from… 
1996
1996
Multiple degradation pathways of the rpsO mRNA of Escherichia coli. RNase E interacts with the 5' and 3' extremities of the primary transcript.
Highly Cited
1994
Highly Cited
1994
mRNA degradation in Escherichia coli: a novel factor which impedes the exoribonucleolytic activity of PNPase at stem‐loop structures
Stem‐loop structures can protect upstream mRNA from degradation by impeding the processive activities of 3′–5′ exoribonucleases… 
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