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PML wt Allele

Known as: PML, TRIM19, MYL 
Human PML wild-type allele is located in the vicinity of 15q22 and is approximately 53 kb in length. This allele, which encodes probable… 
National Institutes of Health

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Related topics

11 relations
15q22Homo sapiensPML geneProbable Transcription Factor PML

Papers overview

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2010
2010
Multicolor monitoring of dysregulated protein kinases in chronic myelogenous leukemia.
The Bcr-Abl and Lyn protein tyrosine kinases have been separately linked to the emergence of imatinib resistance in patients with… 
Highly Cited
2008
Highly Cited
2008
Histone Deacetylase 7 Promotes PML Sumoylation and Is Essential for PML Nuclear Body Formation
ABSTRACT Promyelocytic leukemia protein (PML) sumoylation has been proposed to control the formation of PML nuclear bodies (NBs… 
Highly Cited
2004
Highly Cited
2004
Promyelocytic Leukemia Protein 4 Induces Apoptosis by Inhibition of Survivin Expression*
The promyelocytic leukemia protein (PML) plays an essential role in multiple pathways of apoptosis. Our previous study showed… 
Highly Cited
2000
Highly Cited
2000
Disruption of PML-associated nuclear bodies by IE1 correlates with efficient early stages of viral gene expression and DNA replication in human cytomegalovirus infection.
In human cytomegalovirus (HCMV) infection, both of the major immediate-early proteins IE1(IE68, UL123) and IE2(IE86, UL122… 
Highly Cited
1996
Highly Cited
1996
Barriers to protein folding: formation of buried polar interactions is a slow step in acquisition of structure.
In the MYL mutant of the Arc repressor dimer, sets of partially buried salt-bridge and hydrogen-bond interactions mediated by Arg… 
Highly Cited
1995
Highly Cited
1995
Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix- associated PML bodies
The PML protein was first identified as part of a fusion product with the retinoic acid receptor alpha (RAR alpha), resulting… 
Highly Cited
1994
Highly Cited
1994
Serum cobalamin deficiency is uncommon in multiple sclerosis.
OBJECTIVES To determine the frequency of serum cobalamin (Cbl) deficiency and to clarify the biologic importance of low screening… 
Highly Cited
1992
Highly Cited
1992
Molecular rearrangements of the MYL gene in acute promyelocytic leukemia (APL, M3) define a breakpoint cluster region as well as some molecular variants.
Genomic DNA probes generated from the retinoic acid receptor alpha (RARA) gene located on chromosome 17 and from the MYL gene… 
Highly Cited
1991
Highly Cited
1991
RAR-alpha gene rearrangements as a genetic marker for diagnosis and monitoring in acute promyelocytic leukemia.
Acute promyelocytic leukemias (APLs) are characterized by a translocation that involves chromosomes 15 and 17. The translocation… 
Highly Cited
1968
Highly Cited
1968
Mycoplasma: SUSPECTED ETIOLOGIC AGENT OF CORN STUNT.
Corn stunt, a disease affecting corn (Zea mays L.) and teosinte (Euchlaenia mexicana L.), which causes an economically important… 
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