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PML wt Allele

Known as: PML, TRIM19, MYL 
Human PML wild-type allele is located in the vicinity of 15q22 and is approximately 53 kb in length. This allele, which encodes probable… Expand
National Institutes of Health

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Highly Cited
2009
Review
2008
Review
2008
The promyelocytic leukemia protein (PML) is a tumor suppressor identified in acute PML and implicated in the pathogenesis of a… Expand
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Review
2004
Review
2004
Promyelocytic leukaemia nuclear bodies (PML NBs) are generally present in all mammalian cells, and their integrity correlates… Expand
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Highly Cited
2000
Highly Cited
2000
In human cytomegalovirus (HCMV) infection, both of the major immediate-early proteins IE1(IE68, UL123) and IE2(IE86, UL122… Expand
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Highly Cited
1998
Highly Cited
1998
The PML gene of acute promyelocytic leukaemia (APL) encodes a cell growth and tumour suppressor, however, the mechanisms by which… Expand
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Highly Cited
1998
Highly Cited
1998
The PML gene product is associated with a defined nuclear structure (10-20 per cell) known variously as PML-bodies, ND10, PODs or… Expand
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Highly Cited
1998
Highly Cited
1998
PML is a nuclear protein with growth-suppressive properties originally identified in the context of the PML-retinoic acid… Expand
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Highly Cited
1998
Highly Cited
1998
Inorganic arsenic trioxide (As2O3) and the organic arsenical, melarsoprol, were recently shown to inhibit growth and induce… Expand
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Highly Cited
1995
Highly Cited
1995
The PML protein was first identified as part of a fusion product with the retinoic acid receptor alpha (RAR alpha), resulting… Expand
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Highly Cited
1992
Highly Cited
1992
Acute promyelocytic leukemia (APL) is due to a chromosomal t(15;17) translocation which involves a novel human gene, Myl, (also… Expand
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