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PML wt Allele
Known as:
PML
, TRIM19
, MYL
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Human PML wild-type allele is located in the vicinity of 15q22 and is approximately 53 kb in length. This allele, which encodes probable…
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National Institutes of Health
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Related topics
Related topics
11 relations
15q22
Homo sapiens
PML gene
Probable Transcription Factor PML
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Multicolor monitoring of dysregulated protein kinases in chronic myelogenous leukemia.
Qunzhao Wang
,
E. Zimmerman
,
Alexei Toutchkine
,
Timothy D. Martin
,
L. Graves
,
D. S. Lawrence
ACS chemical biology
2010
Corpus ID: 6968650
The Bcr-Abl and Lyn protein tyrosine kinases have been separately linked to the emergence of imatinib resistance in patients with…
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Review
2008
Review
2008
Regulation of apoptosis by PML and the PML-NBs
R. Bernardi
,
A. Papa
,
P. Pandolfi
Oncogene
2008
Corpus ID: 6489552
The promyelocytic leukemia protein (PML) is a tumor suppressor identified in acute PML and implicated in the pathogenesis of a…
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Review
2004
Review
2004
PML nuclear bodies: dynamic sensors of DNA damage and cellular stress
G. Dellaire
,
D. Bazett-Jones
BioEssays : news and reviews in molecular…
2004
Corpus ID: 25929452
Promyelocytic leukaemia nuclear bodies (PML NBs) are generally present in all mammalian cells, and their integrity correlates…
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Highly Cited
1998
Highly Cited
1998
Pml is essential for multiple apoptotic pathways
Zhu-gang Wang
,
D. Ruggero
,
+4 authors
P. Pandolfi
Nature Genetics
1998
Corpus ID: 35612152
The PML gene of acute promyelocytic leukaemia (APL) encodes a cell growth and tumour suppressor, however, the mechanisms by which…
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Highly Cited
1998
Highly Cited
1998
Arsenic Trioxide and Melarsoprol Induce Programmed Cell Death in Myeloid Leukemia Cell Lines and Function in a PML and PML-RAR Independent Manner
Z. Wang
,
R. Rivi
,
+6 authors
P. Pandolfi
1998
Corpus ID: 208493146
Inorganic arsenic trioxide (As 2 O 3 ) and the organic arsenical, melarsoprol, were recently shown to inhibit growth and induce…
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Highly Cited
1998
Highly Cited
1998
The Promyelocytic Leukemia Gene Product (PML) Forms Stable Complexes with the Retinoblastoma Protein
M. Alcalay
,
L. Tomassoni
,
+6 authors
P. Pelicci
Molecular and Cellular Biology
1998
Corpus ID: 26205347
ABSTRACT PML is a nuclear protein with growth-suppressive properties originally identified in the context of the PML-retinoic…
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Highly Cited
1998
Highly Cited
1998
Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product.
G. Wilkinson
,
C. Kelly
,
J. Sinclair
,
C. Rickards
The Journal of general virology
1998
Corpus ID: 24962735
The PML gene product is associated with a defined nuclear structure (10-20 per cell) known variously as PML-bodies, ND10, PODs or…
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Highly Cited
1996
Highly Cited
1996
Barriers to protein folding: formation of buried polar interactions is a slow step in acquisition of structure.
C. D. Waldburger
,
T. Jonsson
,
R. Sauer
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 20677424
In the MYL mutant of the Arc repressor dimer, sets of partially buried salt-bridge and hydrogen-bond interactions mediated by Arg…
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Highly Cited
1995
Highly Cited
1995
Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix- associated PML bodies
T. Carvalho
,
J. Seeler
,
+5 authors
A. Dejean
The Journal of cell biology
1995
Corpus ID: 11051454
The PML protein was first identified as part of a fusion product with the retinoic acid receptor alpha (RAR alpha), resulting…
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Highly Cited
1992
Highly Cited
1992
Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family…
P. Kastner
,
A. Perez
,
+6 authors
P. Chambon
The EMBO journal
1992
Corpus ID: 46559619
Acute promyelocytic leukemia (APL) is due to a chromosomal t(15;17) translocation which involves a novel human gene, Myl, (also…
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