PMEL gene

Known as: SILV, Silver Homolog (Mouse) Gene, PMEL 
This gene plays a role in melanosome biogenesis. It is also involved in T-cell recognition.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2017
05101519712017

Papers overview

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2014
2014
Multivesicular endosomes/bodies (MVBs) contain intraluminal vesicles (ILVs) that bud away from the cytoplasm. Multiple mechanisms… (More)
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2013
2013
Amyloids are often associated with pathologic processes such as in Alzheimer's disease (AD), but can also underlie physiological… (More)
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Highly Cited
2011
Highly Cited
2011
Cargo sorting to intraluminal vesicles (ILVs) of multivesicular endosomes is required for lysosome-related organelle (LRO… (More)
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2011
2011
PMEL is an amyloidogenic protein that appears to be exclusively expressed in pigment cells and forms intralumenal fibrils within… (More)
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2008
2008
Melanosomes are lysosome-related organelles (LROs) in which melanins are synthesized and stored. Early stage melanosomes are… (More)
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2006
Highly Cited
2006
Merle is a pattern of coloring observed in the coat of the domestic dog and is characterized by patches of diluted pigment. This… (More)
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2005
2005
More than 125 genes that regulate pigmentation have been identified to date. Of those, MART-1 has been widely studied as a… (More)
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2003
Highly Cited
2003
The clinically important melanoma diagnostic antibodies HMB-45, melan-A, and MITF (D5) recognize gene products of the melanocyte… (More)
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2002
2002
Oculocutaneous albinism (OCA) is caused by reduced or deficient melanin pigmentation in the skin, hair, and eyes. OCA has… (More)
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2001
Highly Cited
2001
Melanosomes are tissue-specific organelles within which melanin is synthesized and stored. The melanocyte-specific glycoprotein… (More)
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