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gp100 Antigen

Known as: glycoprotein 100, gp 100, gp100 
A melanoma-associated antigen. When administered in a vaccine formulation, gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Ipilimumab 3 mg/kg was the first agent to demonstrate improved survival in previously treated patients with metastatic melanoma… Expand
Review
2012
Review
2012
Metastatic melanoma is the most aggressive form of skin cancer with a median overall survival of less than one year. Advancements… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Ipilimumab monotherapy (at a dose of 3 mg per kilogram of body weight), as compared with glycoprotein 100, improved… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND An improvement in overall survival among patients with metastatic melanoma has been an elusive goal. In this phase 3… Expand
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Highly Cited
2010
Highly Cited
2010
  • C. Cluff
  • Advances in experimental medicine and biology
  • 2010
  • Corpus ID: 140726
As technological advances allow for the identification of tumor-associated antigens (TAAs) against which adaptive immune… Expand
Highly Cited
2004
Highly Cited
2004
The primary goal of this Phase I study was to assess the safety and bioactivity of tumor lysate-pulsed dendritic cell (DC… Expand
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Review
2000
Review
2000
Diagnostic records from 338 canine oral melanomas in 338 dogs received at the Veterinary Medical Diagnostic Laboratory (1992-1999… Expand
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Highly Cited
1997
Highly Cited
1997
In recent years, it has become evident that T cells can recognize peptides of melanocytic lineage antigens such as gp100, MART-1… Expand
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Review
1983
Review
1983
The selectivity of monoclonal antibody J-5 (anti-gp 100, common ALL antigen) for normal and leukemic hemopoietic cells has been… Expand
Highly Cited
1980
Highly Cited
1980
A monoclonal antibody designated PI153/3, which reacts with neuroblastoma and fetal brain, is shown to identify also a cell… Expand
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