gp100 Antigen

Known as: glycoprotein 100, gp 100, gp100 
A melanoma-associated antigen. When administered in a vaccine formulation, gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
BACKGROUND Ipilimumab monotherapy (at a dose of 3 mg per kilogram of body weight), as compared with glycoprotein 100, improved… (More)
  • table 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Highly Cited
2010
Highly Cited
2010
BACKGROUND An improvement in overall survival among patients with metastatic melanoma has been an elusive goal. In this phase 3… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
As technological advances allow for the identification of tumor-associated antigens (TAAs) against which adaptive immune… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Negative co-stimulatory signaling mediated via cell surface programmed death (PD)-1 expression modulates T and B cell activation… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The primary goal of this Phase I study was to assess the safety and bioactivity of tumor lysate-pulsed dendritic cell (DC… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The alpha- and beta-chains of the TCR from a highly avid anti-gp100 CTL clone were isolated and used to construct retroviral… (More)
Is this relevant?
2003
2003
This report defines a novel approach to heat shock protein vaccine formulation that takes advantage of the chaperoning property… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
In recent years, it has become evident that T cells can recognize peptides of melanocytic lineage antigens such as gp100, MART-1… (More)
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
gp1OO is a melanocytic lineage-specific antigen recognized by tumor-infiltrating lymphocytes, the adoptive transfer of which is… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
gp100 is a melanocyte lineage-specific antigen recognized by tumor-infiltrating lymphocytes whose adoptive transfer has been… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?