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gp100 Antigen

Known as: glycoprotein 100, gp 100, gp100 
A melanoma-associated antigen. When administered in a vaccine formulation, gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Ipilimumab 3 mg/kg was the first agent to demonstrate improved survival in previously treated patients with metastatic melanoma… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Ipilimumab monotherapy (at a dose of 3 mg per kilogram of body weight), as compared with glycoprotein 100, improved… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND An improvement in overall survival among patients with metastatic melanoma has been an elusive goal. In this phase 3… Expand
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Highly Cited
2010
Highly Cited
2010
  • C. Cluff
  • Advances in experimental medicine and biology
  • 2010
  • Corpus ID: 140726
As technological advances allow for the identification of tumor-associated antigens (TAAs) against which adaptive immune… Expand
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Highly Cited
2007
Highly Cited
2007
The aim of this study was to investigate whether depletion of CD4+CD25+ regulatory T cells (Treg) from melanoma patients affects… Expand
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Highly Cited
2004
Highly Cited
2004
The primary goal of this Phase I study was to assess the safety and bioactivity of tumor lysate-pulsed dendritic cell (DC… Expand
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Highly Cited
2000
Highly Cited
2000
Several HLA-A*0201-restricted peptide epitopes that can be used as targets for active immunotherapy have been identified within… Expand
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Highly Cited
1997
Highly Cited
1997
In recent years, it has become evident that T cells can recognize peptides of melanocytic lineage antigens such as gp100, MART-1… Expand
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Highly Cited
1996
Highly Cited
1996
gp1OO is a melanocytic lineage-specific antigen recognized by tumor-infiltrating lymphocytes, the adoptive transfer of which is… Expand
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Review
1983
Review
1983
The selectivity of monoclonal antibody J-5 (anti-gp 100, common ALL antigen) for normal and leukemic hemopoietic cells has been… Expand
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