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Shear stress on arteries produced by blood flow is important for vascular development and homeostasis but can also initiate… Expand Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat… Expand BACKGROUND & AIMS
Little is known about mechanisms of perineural invasion (PNI) by pancreatic ductal adenocarcinomas (PDAs) or… Expand Semaphorins (SEMAs) and their Plexin (PLXN) receptors are central regulators of metazoan cellular communication. SEMA-PLXND1… Expand Möbius syndrome (MBS) is a neurological disorder that is characterized by paralysis of the facial nerves and variable other… Expand Significance PLEXIN D1 (PLXND1) has been implicated in body fat distribution and type 2 diabetes by genome-wide association… Expand Individuals with an inherited deficiency in gonadotropin-releasing hormone (GnRH) have impaired sexual reproduction. Previous… Expand Plexin D1 (PLXND1) is broadly expressed on tumor vessels and tumor cells in a number of different human tumor types. Little is… Expand We previously reported that during mouse embryogenesis, plexin D1 (plxnD1) is expressed on neuronal and endothelial cells… Expand The genetic defect in Möbius syndrome 2 (MBS2, MIM 601471), a dominantly inherited disorder characterised by paralysis of the… Expand