PLPP1 gene

Known as: PHOSPHATIDIC ACID PHOSPHATASE TYPE 2A, LPP1, PAP2A 
This gene is involved in lipid metabolism/transport and receptor-activated signal transduction.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
012319982018

Papers overview

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2012
2012
BACKGROUND Phosphatidate phosphatase (PAP) plays diverse roles in lipid metabolism and cell signaling. RESULTS A novel yeast… (More)
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2012
2012
Partly because of functional genomics, there has been a major paradigm shift from solely thinking of skeletal muscle as… (More)
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2009
2009
LPA (lysophosphatidic acid) is a lipid mediator that stimulates cell proliferation and growth, and is involved in physiological… (More)
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2008
2008
Lipid phosphate phosphatases (LPP1-LPP3) have been topographically modelled as monomers (molecular mass of 31-36 kDa) composed of… (More)
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2008
2008
The sphingolipid metabolite sphingosine 1-phosphate (S1P) plays an essential function in the egress of T cells from the thymus… (More)
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Highly Cited
2001
Highly Cited
2001
Neural tube defects (NTD) are clinically important congenital malformations whose molecular mechanisms are poorly understood. The… (More)
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2000
2000
The product of the LPP1 gene in Saccharomyces cerevisiae is a membrane-associated enzyme that catalyzes the Mg(2+)-independent… (More)
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1999
1999
Two genes in Saccharomyces cerevisiae, LPP1 and DPP1, with homology to a mammalian phosphatidic acid (PA) phosphatase were… (More)
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Highly Cited
1998
Highly Cited
1998
Phosphatidic acid (PA), lysophosphatidic acid, ceramide 1-phosphate (C1P), and sphingosine 1-phosphate (S1P) are lipid mediators… (More)
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1998
1998
The DPP1-encoded diacylglycerol pyrophosphate (DGPP) phosphatase enzyme accounts for half of the Mg2+-independent phosphatidate… (More)
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